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DRUG OF THE DAY > Indapamide > Flashcards

Indapamide Flashcards

1
Q

Drug Class

A

thiazide-like diuretic

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2
Q

Indication

A

Hypertension
Oedema (used over CCB)

take in morning as cause urination that can disturb sleep

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3
Q

Mechanism of Action

A

Inhibits NaCl co-transporter in DCT to decrease sodium & water absorption
Long term effects mediated by sensitivity of smooth muscle to vasoconstrictors (Ca/NA) so vasodilation at lower doses

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4
Q

Adverse Effects

A 
Hypovolaemia 
Hyponatraemia 
Hyperuricaemia (gout)
Arrhythmia 
Increase Glucose & TAG/cholesterol
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5
Q

Contraindications

A

Hypokalaemia
Hyponatraemia
Gout

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6
Q

Drug Interactions

A

NSAIDs

Drugs that decrease potassium (like loop diuretics so electrolyte monitoring needed)

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DRUG OF THE DAY (27 decks)

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