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DRUG OF THE DAY > Omeprazole > Flashcards

Omeprazole Flashcards

1
Q

Drug Class

A

Proton Pump Inhibitor

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2
Q

Common Indications

A

H pylori eradication

gastric & duodenal ulcers (so often given with long term NSAID/steroid)

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3
Q

Mechanism of Action

A

irreversibly inhibits H/K ATPase in gastric parietal cells which is final stage of pathway so significant reduction in acid secretion

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4
Q

Adverse Effects

A

GI disturbance- abdominal pain, constipation/diarrhoea
headaches/dizziness
drowsiness/confusion

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5
Q

Contraindications

A

osteoporosis- fracture risk

masks symptoms of gastrooesophageal cancer

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6
Q

Drug Interactions

A

CYP inhibitor so can reduce clopidogrel action

and PPIs can increase warfarin and phenytoin effects (monitor)

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DRUG OF THE DAY (27 decks)

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