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DRUG OF THE DAY > Cyclizine > Flashcards

Cyclizine Flashcards

1
Q

Drug Class

A

H1 receptor antagonist

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2
Q

Common Indications

A 
Nausea
Vomiting
Vertigo
Motion sickness
Labyrinthine disorders
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3
Q

Mechanism of Action

A

acts on vestibular nuclei to inhibit histaminergic signals from vestibular system to CTZ in medulla

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4
Q

Adverse Effects

A

Sedation
Excitation
antimuscarinic (dry mouth/constipation)
cardiac toxicity * long QT interval *

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5
Q

Drug Interactions

A

lots can increase antimuscarinic effects

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DRUG OF THE DAY (27 decks)

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