Amlodipine Flashcards
1
Q
Drug Class
A
dihydropyridine calcium-channel blocker
2
Q
Common Indications
A
hypertension in low-renin patient
3
Q
Mechanism of Action
A
selective for peripheral vasculature for vasodilation
by preventing influx of calcium —> smooth muscle contraction
Long Half-Life
4
Q
Adverse Effects
A
vasodilation —> ankle swelling, flushing & headaches
compensatory tachycardia —> palpitations
5
Q
Contraindications
A
unstable angina
severe aortic stenosis
6
Q
Drug Interactions
A
amlodipine & SIMVASTATIN (increased effect of statin)
