Metoclopramide Flashcards
1
Q
Drug Class
A
D2 receptor antagonist
2
Q
Common Indications
A
nausea & vomiting
acute migraine
3
Q
Mechanism of Action
A
increases ACh at muscarinic receptors in gut
promotes gastric emptying
increases peristalsis (pro kinetic- good for GORD & ileus)
4
Q
Adverse Effects
A
galactorrhoea (prolactin release) extra pyramidal (dystopia/parkinsonism) as crosses BBB
5
Q
Contraindications
A
obstruction
risk of perforation
6
Q
Drug Interactions
A
prilocaine