Metoclopramide Flashcards

1
Q

Drug Class

A

D2 receptor antagonist

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2
Q

Common Indications

A

nausea & vomiting

acute migraine

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3
Q

Mechanism of Action

A

increases ACh at muscarinic receptors in gut
promotes gastric emptying
increases peristalsis (pro kinetic- good for GORD & ileus)

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4
Q

Adverse Effects

A
galactorrhoea (prolactin release)
extra pyramidal (dystopia/parkinsonism) as crosses BBB
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5
Q

Contraindications

A

obstruction

risk of perforation

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6
Q

Drug Interactions

A

prilocaine

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