Celecoxib Flashcards

1
Q

Drug Class

A

COX 2 inhibitor

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2
Q

Common Indications

A

Analgesic & Anti-inflammatory

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3
Q

Mechanism of Action

A

Inhibits COX2 to decrease prostanoid synthesis

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4
Q

Adverse Effects

A

less GI - dyspepsia, nausea, peptic ulcers, bleeding & perforate
renal - decreased GFR/renal blood flow
increase MI risk in low risk people

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5
Q

Drug Interactions

A

ACEi,ARBs & diuretics

aspirin, glucocorticoid steriouds & anticoagulants (PPIs)

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