Celecoxib Flashcards
1
Q
Drug Class
A
COX 2 inhibitor
2
Q
Common Indications
A
Analgesic & Anti-inflammatory
3
Q
Mechanism of Action
A
Inhibits COX2 to decrease prostanoid synthesis
4
Q
Adverse Effects
A
less GI - dyspepsia, nausea, peptic ulcers, bleeding & perforate
renal - decreased GFR/renal blood flow
increase MI risk in low risk people
5
Q
Drug Interactions
A
ACEi,ARBs & diuretics
aspirin, glucocorticoid steriouds & anticoagulants (PPIs)