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DRUG OF THE DAY > Losartan > Flashcards

Losartan Flashcards

1
Q

Drug Class

A

AT1 receptor blocker or Angiotensin II blocker (ARBs)

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2
Q

Common Indications

A

hypertension

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3
Q

Mechanism of Action

A

directly acts at AT1 receptors
SO more effective inhibiting Ang-II mediated vasoconstriction than ACEi (chymases help produce Ang-II blocked downstream)

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4
Q

Adverse Effects

A

hypotension
hyperkalaemia (low aldosterone)
cause/worsen renal failure

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5
Q

Contraindications

A

pregnancy
renal artery stenosis
AKI
(CKD caution)

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6
Q

Drug Interactions

A

NSAIDS

drugs that increase potassium

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DRUG OF THE DAY (27 decks)

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