Carbamazepine Flashcards
1
Q
Drug Class
A
Anti-Epileptic Drugs
2
Q
Common Indications
A
focal & generalised tonic-clonic seizures
bipolar disorder
3
Q
Mechanism of Action
A
sodium channel blockade in central neurones so slow recovery from inactive to closed & reduced transmission
4
Q
Adverse Effects
A
suicidal thoughts
joint pain
bone marrow failure
(drowsiness, nausea, osteoporosis & Steven Johnson syndrome rash for all AEDs)
5
Q
Drug Interactions
A
CYP inducer (warfarin)
alcohol
decreased effectiveness of oral contraceptives/antibiotics