Carbamazepine Flashcards

1
Q

Drug Class

A

Anti-Epileptic Drugs

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2
Q

Common Indications

A

focal & generalised tonic-clonic seizures

bipolar disorder

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3
Q

Mechanism of Action

A

sodium channel blockade in central neurones so slow recovery from inactive to closed & reduced transmission

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4
Q

Adverse Effects

A

suicidal thoughts
joint pain
bone marrow failure
(drowsiness, nausea, osteoporosis & Steven Johnson syndrome rash for all AEDs)

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5
Q

Drug Interactions

A

CYP inducer (warfarin)
alcohol
decreased effectiveness of oral contraceptives/antibiotics

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