Sepsis Flashcards
what is sepsis
is caused by the way the body responds to an infection which can lead to: hypotension, shock, organ failure, death
dysregulation of host response to infection
what can organ failure be represented by
sequential organ failure assessment SOFA score of greater than 2
what types of sepsis shock are there
circulatory, cellular and metabolic
what are the hospital mortality rates for septic shock
greater than 40%
in the qSOFA score what 3 characteristics provide poor outcomes for patients
reparatory rate greater than 22
altered mentation
systolic blood pressure less than 100
what 4 biological pathologies does sepsis lead to
endothelial dysfunction
coagulopathy
cellular dysfunction
cardiovacular dysfunction
what types of pathologies are associated with multiple organ filature in sepsis
acute lung injury hypotension AKI gastrointestinal mucosal injury liver dysfunction
what kind of people are most vulnerable to sepsis
younger than 1 and older than 75 frail people impaired immunity recent trauma or surgery catheter users breaches of skin integrity
what are some recognition factors of sepsis
symptoms of infection such as temperature or productive cough
non-specific and non localising presentations such as simply feeling unwell
concerns presented by family about the patient
what are the high risk criteria patient for sepsis
new altered mental state
reparatory rate over 25
need for oxygen where 40% FiO2 needed to maintain 92% saturation
heart rate greater than 130 beats per min
systolic blood pressure lower than 90 or 40 lower than normal
not passed urine in 18 hours
cyanosis
non-blanching rash
what system is used to identify sepsis
NEWS2
what responses should be carried out if you suspect sepsis interns of blood and culture
carry out venous blood test for the following: blood gas including glucose and lactate measurement blood culture full blood count c reactive protein urea and electrolytes creatinine clotting screen
culture:
sputum, urine, wound, wound swab
what should be given to the patient within one hour of high risk criteria of sepsis
intravenous fluids and antibiotics
what is the sepsis buffalo
B - blood cultures with screen U - urine output F - fluid resuscitation A - antibiotics IV L - lactate measurement from blood gas O - oxygen (correct hypoxia)
why do you provide resuscitation fluids
to correct hypovolaemia
