Rickets Flashcards
What is Ricketts?
Clinical manifestation of calcium, phosphate or vitamin D deficiency in children
What type of genetic condition is Ricketts?
X-linked dominant condition
How does Rickett’s present?
- Poor growth and development
- Muscle weakness
- Bone and joint pain
- Constipation
- Delayed dentition
What bone deformities can occur in Rickets?
- Craniotabes
- Bow knees
- Knock knees
- Rachitic Rosary
How would you diagnose Rickets?
- X-ray
- 25-hydroxyvitaminD
- Calcium and phosphate deficiency
- PTH and ALP raised
What would you see on an x-ray of someone with Rickets?
Widened epiphyseal plate
What would the level of 25-hydroxyvitaminD be to diagnose Rickets?
Less than 25ng/mol
What are risk factors for Rickets?
Malabsorption
Chronic kidney disease
Lack of sun exposure
Poor nutrition
What can malabsorption be due to?
Coeliac
IBD
What is the management of Rickets?
Oral vitamin D
What does Falconi syndrome include?
- Type 2 renal tubular acidosis
- Rickets/osteomalacia
- Polyuria
What is the main cause of Rickets?
Prolonged lack of sufficient vitamin D
What can a prolonged lack of vitamin D result in?
An inability to absorb calcium and phosphorous from food.
