Respiratory System Flashcards
CONDUCTING PORTION
● Nasal cavities
● Pharynx
● Larynx
● Trachea
● Bronchi, bronchioles, terminal bronchioles
gas exchange
RESPIRATORY PORTION
RESPIRATORY PORTION:
● Respiratory bronchioles
● Alveolar ducts
● Alveoli
the cellular sites of the exchange of O2 and CO2 between inspired air and blood, are small, air-filled, saclike structures, which make up most of the lung structure.
ALVEOLI
The left and right nasal cavities each have two components:
external dilated vestibule
internal nasal cavity
The skin of the nose enters the _______ into the _____ and includes sweat glands, sebaceous glands, and coarse, moist vibrissae (hairs), which filter out particulate material from inspired air
nares (nostrils) partway
vestibule
The _____ lie within the skull as two cavernous chambers separated by the osseous nasal septum.
nasal cavities
Extending from each lateral wall are three bony shelflike projections called
conchae, or turbinate bones.
RESPIRATORY EPITHELIUM:
Nasal cavities and conducting portion
ciliated pseudostratified columnar epithelium
Most of the nasal cavities and conducting portion of the system is lined with mucosa having ciliated pseudostratified columnar epithelium commonly known as the ______.
respiratory epithelium
Respiratory epithelium five major cell types:
most abundant, 250-300 cilia
CILIATED COLUMNAR CELLS
Respiratory epithelium five major cell types:
move microbes and debris up and out of airways
CILIATED COLUMNAR CELLS
Respiratory epithelium five major cell types:
Numerous and predominate in some areas with basal nuclei and apical domain
GOBLET CELLS
Respiratory epithelium five major cell types:
with granules of mucin glycoprotein
GOBLET CELLS
Respiratory epithelium five major cell types:
secrete mucin and create protective mucus layer
GOBLET CELLS
Respiratory epithelium five major cell types:
much less numerous
BRUSH CELLS
Respiratory epithelium five major cell types:
columnar cell type
BRUSH CELLS
Respiratory epithelium five major cell types:
sparse, blunt microvilli
BRUSH CELLS
Respiratory epithelium five major cell types:
chemosensory receptors resembling gustatory cells
BRUSH CELLS
Respiratory epithelium five major cell types:
detect small particles of bacterial protein
BRUSH CELLS
Respiratory epithelium five major cell types:
difficult to distinguish in routine preparations
SMALL GRANULE CELLS (KULCHITSKY CELLS)
Respiratory epithelium five major cell types:
possess numerous dense core granules 100-300 nm in diameter
SMALL GRANULE CELLS (KULCHITSKY CELLS)
Respiratory epithelium five major cell types:
are part of the diffuse neuroendocrine system (DNES)
SMALL GRANULE CELLS (KULCHITSKY CELLS)
Respiratory epithelium five major cell types:
represent 3% of the cells
SMALL GRANULE CELLS (KULCHITSKY CELLS)
Respiratory epithelium five major cell types:
production of lipid for the mucus layer above epithelium
SMALL GRANULE CELLS (KULCHITSKY CELLS)
Respiratory epithelium five major cell types:
mitotically active stem and progenitor cells
BASAL CELLS
Respiratory epithelium five major cell types:
give rise to other epithelial cells
BASAL CELLS
Chemoreceptors for the sense of smell are located in the
olfactory epithelium
specialized region of the mucous membrane covering the superior conchae at the roof of the nasal cavity
OLFACTORY EPITHELIUM
are bipolar neurons present throughout this epithelium.
OLFACTORY NEURONS
nuclei form an irregular row near the middle of this thick epithelium.
OLFACTORY NEURONS
apical (luminal) pole of each olfactory cell is its dendrite end and has a knoblike swelling with about a dozen basal bodies, from which long cilia project into the overlying aqueous layer
OLFACTORY NEURONS
These cilia have nonmotile axonemes and collectively provide a large surface for transmembrane chemoreceptors
OLFACTORY NEURONS
The receptors respond to ______ by generating an action potential along the axons extending from the basal ends of these neurons
odoriferous substances
The axons leave the epithelium and unite in the lamina propria as very small nerves that then pass to the brain through foramina in the cribriform plate of the ethmoid bone.
OLFACTORY NEURONS
are columnar, with narrow bases and broad, cylindrical apexes containing the nuclei and extending microvilli into the fluid layer
SUPPORTING CELLS
Well-developed junctional complexes bind the supporting cells to the olfactory cells
SUPPORTING CELLS
Well-developed junctional complexes bind the supporting cells to the olfactory cells
SUPPORTING CELLS
they express abundant ion channels, which help maintain a microenvironment conducive to olfactory function and survival.
SUPPORTING CELLS
are small, spherical, or cone-shaped cells near the basal lamina.
BASAL CELLS
These are the stem cells for the other two types, replacing the olfactory neurons every 2-3 months and support cells less frequently
BASAL CELLS
are bilateral cavities in the frontal, maxillary, ethmoid, and sphenoid bones of the skull
PARANASAL SINUSES
are lined with a thinner respiratory epithelium having fewer goblet cells.
PARANASAL SINUSES
Unlike the stratified squamous epithelium of the oropharynx, the ______ is the respiratory epithelium, and its mucosa contains the medial pharyngeal tonsil and the openings of the two auditory tubes which connect to each middle ear cavity.
nasopharynx lining
PHARYNX:
OROPHARYNX
NASOPHARYNX
PHARYNX:
stratified squamous epithelium
OROPHARYNX
PHARYNX:
Respiratory epithelium
NASOPHARYNX
PHARYNX:
Ciliated pseudostratified columnar epithelium
NASOPHARYNX