Epithelium and Glands (PPT based) Part II Flashcards
Nexus or communicating junctions
GAP JUNCTION
Couple adjacent cells metabolically and electrically
GAP JUNCTION
Common in certain tissues like CNS, cardiac and smooth muscles
GAP JUNCTION
Gap junction is composed of a channel-forming proteins (connexins) that assemble to form _______
connexons
Extracellular supporting structure
BASAL LAMINA
Produce by epithelium
BASAL LAMINA
Composed of type IV collagen, laminin, entacin, proteoglycans (mostly heparin sulfate)
BASAL LAMINA
Located at the boundary between epithelial cells and the underlying connective tissue
BASAL LAMINA
Specialized junctions that resemble ½ of the macula adherens
HEMIDESMOSOMES
Mediate adhesion of basal cell membrane to basal lamina
HEMIDESMOSOMES
Integrins on one side is attached to the plaque with keratin tonofilaments and on the other side attaches to laminin and collagen IV of BL
HEMIDESMOSOMES
Finger-like enfoldings functions to increase the surface area available for transport
BASAL PLASMA-MEMBRANE ENFOLDINGS
Common in ion-transporting epithelia
BASAL PLASMA-MEMBRANE ENFOLDINGS
Examples of basal plasma-membrane enfoldings:
Distal convoluted tubules, ducts in salivary glands
Compartmentalize mitochondria
BASAL PLASMA-MEMBRANE ENFOLDINGS
Function to bring ion pumps close to their energy supply (mitochondria)
BASAL PLASMA-MEMBRANE ENFOLDINGS
CLASSIFICATION OF EPITHELIA:
based on cell layer
Simple (one layer)
Stratified (more than one cell layer)
Classification of epithelia:
Based on cell morphology
Squamous
Cuboidal
Columnar
Other classification of epithelia:
Pseudostratified
Transitional