Connective Tissue Part III Flashcards
Enumerate the bone growth in length
- Zone of reserve cartilage
- Zone of proliferation
- Zone of maturation and hypertrophy
- Zone of calcification
- Zone of ossification
Flat bones of the skull and mandible are formed in this way
Intramembranous ossification
“Soft spots” that help the fetal skull pass through the birth canal later become ossified forming the skull
Intramembranous ossification
The replacement of cartilage by bone
Endochondral ossification
Most bones of the body are formed in this way including long bones
Endochondral ossification
An ossification center appears in the fibrous connective tissue membrane
Intramembranous Ossification
Osteoblasts secrete bone matrix within the fibrous membrane
Intramembranous Ossification
Osteoblasts mature into osteocytes
Intramembranous Ossification
Replacement of hyaline cartilage with bone Most bones are formed this way (i.e. long bones).
Endochondral Ossification
BONE GROWTH IN LENGTH:
Chondrocytes randomly distributed throughout the matrix
Zone of reserve cartilage
BONE GROWTH IN LENGTH:
Chondrocytes proliferating, form rows of isogenous cells in parallel direction
Zone of proliferation
BONE GROWTH IN LENGTH:
Chondrocytes mature, hypertrophy and accumulate glycogen
Zone of maturation and hypertrophy
BONE GROWTH IN LENGTH:
Lacunae becomes confluent, hypertrophied chondrocytes die and cartilage matrix calcified
Zone of calcification
BONE GROWTH IN LENGTH:
Osteoprogenitor-osteoblast-osteocyte-calcification
Zone of ossification
BONE GROWTH IN LENGTH:
Osteoprogenitor-osteoblast-osteocyte-calcification
Zone of ossification
