Muscle Part II Flashcards
Motor unit is consists of:
neuron
muscle cell it innervates
A muscle may contract with varying degrees of strength because only some of the muscle cell contracts.
MOTOR UNIT
Individual muscle cell – “all or none law”
MOTOR UNIT
Finer muscle movements require fewer muscles per motor unit (eye movement)
MOTOR UNIT
Motor nerve endings (MNJ) and sensory nerve endings (muscle spindles and Golgi tendon organs for proprioception)
INNERVATION OF SKELETAL MUSCLE
synapse between a branch of a motor nerve axon and a skeletal muscle cell
Myoneural junction
Depol presynaptic memb 🡪 Ca channels open 🡪 inc cytosolic Ca 🡪 Ach released 🡪 bind to Ach receptors in sarcolemma 🡪 depol
INNERVATION OF SKELETAL MUSCLE
Postmortem rigidity appearing as hardening of skeletal muscles
RIGOR MORTIS
Unable to synthesize ATP 🡪 myosin remains bound to actin 🡪 muscles remain contracted
RIGOR MORTIS
Sensory receptors that monitor contraction:
Muscle spindles
Golgi tendon organs
provides feedback about changes in muscle length and its rate of alteration
Muscle spindles
monitor the tension and its rate produced during movement
Golgi tendon organs
autoimmune disease in which antibodies block Ach receptors
Myasthenia gravis
food poisoning in which Clostridium botulinum toxin inhibits Ach release at MNJ
Botulism
Example of this is Botox cosmetic procedure
Botulism
Shape and size of cells of skeletal muscle:
Long, cylindrical
How many number and location of nucleus are there in a skeletal muscle?
Many, peripheral
Is there a striations in a skeletal muscle?
Yes
Property of skeletal muscle: T-tubules, sarcoplasmic reticulum
Triads at A-I junctions