Connective Tissue Part III Flashcards
dense layer forms the outside of the bone
compact bone
spongelike meshwork consisting of trabeculae
spongy bone (cancellous bone)
The spaces within the meshwork are continuous and occupied by marrow and blood vessels.
spongy bone (cancellous bone)
longer in one dimension
e.g., humerus, femur
Long bones
nearly equal in length and diameter
Short bones
Have compact, spongy bone and a marrow space on the inside
Short bones
Articular surfaces are covered with hyaline cartilage
Short bones
Examples are carpals, tarsals, patella
Short bones
thin and platelike bones
Flat bones
Examples are parietal bone, scapula, sternum
Flat bones
Thick compact bone with an intervening layer of spongy bone
Flat bones
Examples are vertebrae, hip bones, ethmoid bone
Irregular bones
tendons
Sesamoid bones
Is an outer fibrous sheath of dense regular connective tissue covering of the bone except articular surface.
Periosteum
Two layers of Periosteum
outer fibrous layer
an inner cellular (osteogenic) layer
is well defined If active bone formation is in progress
inner cellular (osteogenic) layer of Periosteum
The relatively few ______ are capable of undergoing division and becoming osteoblasts under appropriate stimulus.
periosteal cells
Collagen fibers from ligaments and tendons extend directly into the bone tissue, where they are continuous with the collagen fibers of the extracellular matrix of the bone tissue.
Sharpey’s fibers
The marrow cavity and the spaces in spongy bone contain ____
bone marrow
normally restricted to the spaces of spongy bone in the adult
Red bone marrow
consists mostly of fat cells
yellow marrow
can revert to red marrow e.g. extreme blood loss
yellow marrow
Mature Bone/Lamellar bone is composed of cylindrical units called
Osteons or Haversian systems
osteons consist of concentric lamellae of bone matrix surrounding a central canal, the osteonal (Haversian) canal, which contains the vascular and nerve supply of the osteon.
Mature Bone/lamellar bone
Within the bone matrix are spaces called ______, each containing osteocyte.
lacunae
The osteocyte extends numerous processes into small tunnels called ________.
canaliculi
communicate by gap junctions with other osteocytes
canaliculi
generally arranged in a radial pattern with respect to the Haversian canal
canaliculi
serves for the passage of substances between the osteocytes and blood vessels
canaliculi
Between the osteons are remnants of previous concentric lamellae called
interstitial lamellae
_______ follow the entire inner and outer circumferences of the shaft of a long bone
Circumferential lamellae
This is where blood vessels and nerves travel from the periosteal and endosteal surfaces to reach the osteonal canal; they also connect osteonal canals to one another
Perforating canals (Volkmann’s canals)
not surrounded by concentric lamellae
Perforating canals (Volkmann’s canals)
CELLS OF BONE TISSUE:
osteoprogenitor cells,
osteoblasts,
osteocytes,
Osteoclasts
bone tissue Cells are surrounded by matrix
- ____ water
- ____ protein
- ____ mineral salts
25%
25%
50%
derived from mesenchymal stem cells
Osteoprogenitor Cells
is a resting cell that can differentiate into an osteoblast and secrete bone matrix
Osteoprogenitor Cells
Morphologically, they comprise the periosteal cells that form the innermost layer of the periosteum and the endosteal cells that line the marrow cavities, the osteonal (Haversian) canals, and the perforating (Volkmann’s) canals.
Osteoprogenitor Cells
is the differentiated bone-forming cell that secretes bone matrix /type I collagen and bone matrix proteins (BMPs)
Osteoblast
processes communicate with other osteoblasts and with osteocytes by gap junctions.
Osteoblast
Are mature bone cells derived from osteoblasts that became trapped in lacunae
Osteocytes
They are responsible for maintaining the bone matrix.
Osteocytes
synthesize new matrix, as well as participate in matrix degradation → maintain calcium homeostasis
Osteocytes
arranged with their long axes in the same direction as the lamellae.
Osteocytes
Are multinucleated cells originating from granulocyte-macrophage progenitors
Osteoclasts
Play a role in bone resorption
Osteoclasts
Are bone-resorbing cells present on bone surfaces where bone is being removed or remodeled
Osteoclasts
a shallow bay called a _________ can be observed in the bone directly under the osteoclast.
resorption bay (Howship’s lacuna)