Reproductive Physiology Flashcards
What are gametes?
Haploid reproductive cells, each with half the normal chromosome count
How many chromosomes do haploid cells have?
23
What are the male and female gametes?
Spermatozoa
Ova
How are gametes produced?
meiosis
What are somatic cells?
fully operational diploid cells that have 46 chromosomes
What is fertilization?
fusion of two games to form a zygote
What is meiosis?
DNA replication that has two nuclear divisions to produce 4 gametes from one reproductive stem cell
What is meiosis 1?
First round of cell division to create genetic variation
What is DHT?
Dihydrotestosterone, singals for development of penis and scrotum
What is spermatogenesis?
process of producing male gametes
Where does spermatogenesis occur?
seminiferous tubules of testes
How long does spermatogenesis take?
64 days
How much sperm does spermatogenesis produce?
100 million/day
What are the stages of spermatogenesis?
Mitotic proliferation
Meiosis
Packaging
What is mitotic proliferation?
Continuous mitosis of diploid spermatogonia
What is packaging?
break down and construction to create sperm with head, midpiece, and tail
What does GnRH do in males?
stimulates release of LH and FSH from anterior pituitary
What does FSH do in males?
stimulates spermatogenesis via sertoli cells
What does LH do in males?
stimulates testosterone secretion via Leydia cells
What are Sertoli cells?
produce inhibin, negative feedback on FSH
What are Leydia cells?
produce testosterone, negative feedback on LH
How does erection occur?
PNS induced nitric oxide causes vasodilation
How does ejaculation occur?
SNS contraction
What is oogenesis?
process of forming females gametes from germ cells
What are the stages of oogenesis?
mitotic proliferation
meiosis 1 and 2
ovulation
fertilization
What are thecal cells?
respond to LH
What are granulosa cells?
resond to FSH
What are the follicle types?
Primary Secondary Graafian Corpus luteum Corpus albicans
What do primary follicles secrete?
all present at birth
waits for hormones
What do secondary follicles secrete?
to be matured
What does estrogen do?
stimulates follicle growth and maturation
What is peak estrogen secretion?
stimulates uterine lining thickening
What does corpus luteum secrete?
progesterone
What does progesterone?
further thickens lining, blood vessels and secretion of mucus
What is the LH burst?
triggers ovulation
What does GnRH do in females?
triggers release of FSH and LH from the anterior pituitary
What does FSH do in females?
stimulates the development of follicles
What does LH do in females?
stimulates the development of follicles
What do developing follicles secrete?
low levels of estrogen and inhibin which have negative feedback on FSH
What is the ovarian cycle?
state of follicles and hormone secretion cycles each month
What is the follicular phase?
FSH and LH rise, stimulate oocyte development and follicle growth
Estrogen slowly rises and then peaks
What is the ovulation phase?
FSH and LH peak due to high estrogen, LH burst triggers ovulation
What is the luteal phase?
LH and FSH decline, progesterone rises and peaks
What is the uterine cycle?
The cycle of thickening endometrium in the uterus
What is the menstrual phase?
if fertilization has not occured, lining is shed
What is the proliferative phase?
uterine lining thickens in response to estrogen increase
What is the secretory phase?
uteine lining becomes thick and secretory due to progestrone
What is epispadias?
Upward curvature of penis, urinary opening not at tip
What is hypospadias?
Downward curvature of penis, urinary opening not at tip
What is Peyronie’s disease?
Curvature of the shaft of the penis due to injury
What is AIS?
Intersex condition where XY human cells dont respond to testosterone
What are the levels of AID?
Complete (this one is mistaken for a female)
Mild
Partial
What is Klinefelter syndrome?
XXY
Infertile, tall with small testes that produce reduced testosterone
What is Turner syndrome?
XO
Short webbed neck, hormone treatment required to develop normal female breasts and periouds
What does the Graafian follicle?
1-2 complete maturation
multiple layers
What is the corpus albicans?
degenerating follicel