Nervous Physiology 2 Flashcards

1
Q

What are precursors?

A

simple amino acids from the diet that help build NTs

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2
Q

What are the NT categories based on chemistry?

A
CAMP
Cholines
Amino acids
Monoamines (biogenic amines)
Peptides
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3
Q

What are the NT categories based on function?

A

Excitatory NT - create EPSP
Inhibitory NT - create IPSP
(many have both)

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4
Q

What are monamines?

A

Most extensive set of NT that are modified amino acids

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5
Q

What are the catecholamines?

A

Norepinephrine
Epinephrine
Dopamine

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6
Q

What is histamine?

A

Crucial role in wound healing and allergies

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7
Q

What is serotonin?

A

Regulates stress and emotions like anxiety, depression, memory

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8
Q

What are adrenergic nerves?

A

Those that produce monamines

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9
Q

What are examples of amino acid NTs?

A

GABA
Glycine
Glutamine

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10
Q

What is glutamate?

A

excitatory NT, essential in learning and long term memory

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11
Q

What is GABA?

A

most abundant inhibitory NT in the brain, regulates neuronal activity, anxiety, sleep

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12
Q

What is glycine?

A

inhibitory NT, inhibition of antagonistic muscles in spinal reflexes

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13
Q

What are peptide NTs?

A

Short-chain amino acids, mostly function in pain, emotion, food intake

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14
Q

Where is peptide NT synthesized?

A

Rough ER, transported in its own vesicle down the axon to the terminal

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15
Q

Where are other NTs synthesized?

A

Cytoplasm of nerve cell terminal and stored in vesicles

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16
Q

Where are choline-based NTs made?

A

Synthesized in neurons from choline and acetyl CoA

17
Q

How do Choline based NTs function?

A

act on the muscarinic and nicotinic receptors

18
Q

What is acetylcholine?

A

First NT to be identified, most studied, both excites and inhibits

19
Q

How does acetylcholine affect Alzheimer’s?

A

Inadequate amount found in people that have Alzheimer’s

20
Q

When do dreams occur?

A

during REM sleep when ACh levels are high

21
Q

What do agonist drugs do?

A

enhance NTs

22
Q

What do antagonistic drugs do?

A

block/inhibit NT activity

23
Q

What do impaired GABA receptors do?

A

cause anxiety, panic attacks, seizures, Parkinson’s

24
Q

What is another name for glutamate?

25
What do impaired glutamate receptors do?
result in intellectual disabilities, Alzheimer's, ALS
26
What is serotonin made from?
tryptophan
27
What does serotonin effect?
emotion, sleep, appetite, mood, and perception
28
What does Prozac do?
prevents reuptake (SSRI), same as warm milk
29
What does norepinephrine do?
involved in fight-or-flight, agonistic drugs enhance it, it effects attention, concentration, control of temp, and pituitary gland
30
What does dopamine do?
inhibitory or excitatory, please and elation, key to addiction, inadequate levels can lead to ADHD and Parkinson's
31
What is a ganglion?
cluster of nerves in the PNS
32
What are sympathetic fiber?
adrenergic
33
What are parasympathetic fibers?
cholinergic
34
What is the only autonomic transmitter that is NE?
Post Sympathetic
35
What are monosynaptic reflex arcs?
arcs made of only two neurons
36
What does an autonomic reflex arc do?
affect organs
37
What does a somatic reflex arc do?
affect muscles