Renal Failure Flashcards
What are the important conditions associated with Renal Failure
Chronic renal failure
Acute renal failure
What are the usual causes of chronic renal failure?
From “wearing out” of the kidney
Does the kidney regenerate like the liver?
No
What percentage of nephrons are destroyed before an increase in BUN/Creatinine?
75%
In what species and age group is chronic renal failure common in?
Older cats
Chronic Renal failure
Usually idiopathic
Irreversible and progressive
What are the symptoms of chronic renal failure?
ADR Weight loss Inappetence Lethargy PU/PD
What is acute renal failure?
Abrupt shutdown of the kidney function
What are the characteristics of acute renal failure?
Oliguria
Can be reversible or fatal
What are the causes of acute renal failure?
Nephrotoxins Drugs Infections Trauma Dehydration Hemorrhage
What is an example of a nephrotoxin?
Antifreeze poisoning
What are some examples of drugs that can cause acute renal failure?
Aspirin
Acetaminophen
Ibuprofen
Naproxen
What is an example of an infection that can cause acute renal failure?
Leptospirosis
What is the difference between chronic renal failure and acute renal failure?
CRF is not reversible while ARF can be depending on the cause and response to treatment
What are the other considerations when differentiating between chronic and acute renal failure?
The physical condition of the patient
The history and exposure to toxins and drugs
Any lab differences
What does the bloodwork of a chronic renal failure patient look like?
Anemia
high SDMA, BUN, Creatinine
hypokalemia
Acidodic
What does the bloodwork of an acute renal failure patient look like?
Normal PCV
High SDMA, BUN, Creatinine
Hyperkalemia
High phosphorus
What does the urinalysis of a chronic renal failure patient look like?
Dilute
Proteinuria
Normal sediment
What does the urinalysis of an acute renal failure patient look like?
Dilute
Proteinuria
Active urine sediment with WBCs, casts and crystals
What is a renal function test in birds?
Uric Acid
What breed has a defect in the uric acid uptake into the hepatocytes?
Dalmations
What do Dalmations not convert?
uric acid does not convert to allantoin
Excrete uric acid in urine