Miscellaneous Tests Flashcards
Creatine kinase (CK)
One of the most organ-specific enzymes available for clinical evaluation
Where is creatine kinase produced?
Striated muscle cells and to some extent in the brain
Where does creatine kinase leak out of?
Damaged muscles into the blood
Can you determine which muscle is damaged with CK?
NO
What is grouped with the liver leakage enzymes as a rule-out test?
CK along with AST, ALT
What comes from the liver and also from the skeletal muscle?
AST and ALT
What do you know if CK is elevated?
Some of the AST/ALT came from the muscle, not the liver
What do you know if CK is normal?
Elevations in AST/ALT came from the liver
What is produced by anaerobic cellular metabolism?
Lactic acid
What does an elevated lactic acid indicate?
Hypoxia or hypoperfusion