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Imunologia > Qual é a Doença e o Anticorpo? > Flashcards

Qual é a Doença e o Anticorpo? Flashcards

1
Q

Anticorpos anti-nucleares (ANA)

A 
Lúpus Eritematoso Disseminado
Lúpus Eritematoso Medicamentoso
Síndrome de Sjögren
Doença mista do tecido conjuntivo
Poliomiosite
Dermatomiosite
Hepatite auto-imune de tipo I
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2
Q

Ac Anti-nucleossomas

A

Lúpus eritematoso sistémico

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3
Q

Ac Anti-ENA (Sm, RNP, SSA, SSB)

A

Lúpus eritematoso sistémico

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4
Q

Ac Receptores da TSH (TRABs)

A

Graves

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5
Q

Ac Anti-21-Hidroxilase

A

Doença de Addison

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6
Q

Anticorpos Anti-SSA

A

Lúpus Cutâneo Subagudo
Lúpus Eritematoso Sistémico
Síndrome de Sjögren

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7
Q

Ac Anti-Ku

A

Lúpus Eritematoso Disseminado
Poliomiosite
Dermatomiosite

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8
Q

Ac Anti-RNP

A

Doença Mista do Tecido Conjuntivo

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9
Q

Ac Anti-SSA/SSB

A

Síndrome de Sjögren

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10
Q

Anti-Scl70

A

Esclerodermia Sistémica Progressiva

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11
Q

Ac Anti-Centrómero

A

CREST

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12
Q

Quais são os anticorpos do SíndromeAntifosfolipídico?

A

Anti-cardiolipina
Anti-Beta2 Glicoproteína I
Anticoagulante lúpico

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13
Q

No Lúpus, procuramos que anticorpos?

A 
ANA
Anti-dsDNA
Anti-Nucleossomas
Anti-ENA (Sm, RNP, SSA, SSB)
Anti-Ribossomal P Protein
Anti- Ku
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14
Q

Anti-Fibrilharina

A

Esclerodermia sistémica progressiva

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15
Q

Factor Reumatóide (classicamente - IgM)

A

Artrite Reumatóide

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16
Q

Ac. Anti Péptido Citrulinado Cíclico

A

Artrite Reumatóide

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17
Q

Principal teste para artrite reumatóide

A

Anti-Péptido Citrulinado Cíclico

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18
Q

Ac Anti Cardiolipina

A

SAAF

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19
Q

Anti-PM-Scl

A

Poliomiosite

Dermatomiosite

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20
Q

Ac Anti-Mitocôndriais (AMA) fazem pesquisar…

A

Cirrose Biliar Primá´ria

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21
Q

Quais são os dois anticorpos importantes de se pesquisar na Cirrose Biliar Primária?

A

Anti-M2 (PDH)

Anti-BPO (3E)

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22
Q

Ac. Anti-Factor Intrínseco

A

Anemia Perniciosa

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23
Q

Ac. Anti-Células Parietais (APCA)

A

Gastrite Autoimune

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24
Q

Ac Anti-M2 (PDH)

A

Cirrose Biliar Primária

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25
Q

Ac Anti-BPO (3E)

A

Cirrose Biliar Primária

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26
Q

Ac Anti-Fibras de Actina (f-actina)

A

Hepatite auto-imune I

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27
Q

Ac Anti-NANA ou p-ANCA atípico

A

Colangite Esclerosante Primária

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28
Q

Anticorpos da DM I

A

Anti-Ilhéus de Langerhans (ICA)
Anti-Descarboxilase Glutâmica 65 (GAD65)
Anti-Fosfatase da Tirosina (IA2)
Anti-Insulina (IIA)

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29
Q

Anti-Transglutaminase (tTG)

A

Doença Celíaca

Dermatite herpetiforme

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30
Q

Ac Anti Beta2 Glicoproteina I

A

SAAF

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31
Q

Anti-Saccharomyces cervisae (ASCA)

A

Crohn

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32
Q

Anti-Endomísio

A

Doença Celíaca

Dermatite herpetiforme

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33
Q

Anti-Células de Goblet

A

Colite Ulcerosa

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34
Q

Anti-Pâncreas exócrino

A

Crohn

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35
Q

Anti-Gliadina

A

Doença Celíaca

Dermatite herpetiforme

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36
Q

Anti-pANCA

A

Colite Ulcerosa

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37
Q

Anti-LC-1

A

Hepatite auto-imune II

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38
Q

Anti-Reticulina (ARA1)

A

Doença Celíaca

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39
Q

Anti-LKM 1

A

Hepatite auto-imune II

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40
Q

Anti-gp210

A

Cirrose Biliar Primária

41
Q

Anti-Tiroperoxidase (TPO)

A

Hashimoto (principalmente)

42
Q

Anticorpos Anti-Membrana Basal Glomerular

A

Síndrome de Goodpasteur

43
Q

Anti-cANCA tipo Antiproteinase 3 (PR3)

A

Doença de Wegener

44
Q

Anti-Tiroglobulina

A

Hashimoto (principalmente)

45
Q

Na tiroidite de Hashimoto, pesquisamos…

A

Anti-Tiroperoxidase (TPO)

Anti-Tiroglobulina (ATg)

46
Q

Anti-pAnca tipo Mieloperoxidase (MPO)

A

Poliangeite Microscópica

47
Q

Anti-Substância Intercelular (desmossomas)

A

Pênfigo

48
Q

Manifestação cutânea típica da doença celíaca

A

Dermatite Herpetiforme

49
Q

Anticorpos típicos da dermatite herpetiforme

A

Anti-Gliadina
Anti-Endomísio
Anti-Transglutaminase

50
Q

Ac. Anti-Ovários estão associados a…

A

Menopausa precoce

51
Q

Ac Anti Membrana basal epidérmica

A

Pênfigo bulhoso

52
Q

Anticoagulante lúpico

A

SAAF

53
Q

Anti-RNA polimerase I

A

Esclerodermia sistémica progressiva

54
Q

Anti-Mi

A

Poliomiosite

Dermatomiosite

55
Q

Anti PL7 e Anti PL12

A

Poliomiosite

Dermatomiosite

56
Q

Anti-NOR90

A

Esclerodermia Sistémica Progressiva

57
Q

Anti-Descarboxilase Glutâmica 65 (GAD65)

A

DM I

58
Q

Numa doente com menopausa precoce, pesquisamos…

A

Ac Anti-Ovários

59
Q

Ac. Anti-Receptores de Ach

A

Miastenia

60
Q

Anti-dsDNA

A

Lúpus eritematoso disseminado

61
Q

Ac Anti-Ribossomal P Protein

A

Lúpus eritematoso sistémico

62
Q

Ac Anti Canais de Cálcio

A

Sínd. Eaton-Lambert (carcinoma de pequenas células do pulmão!)

63
Q

Ac Anti-Músculo estriado

A

Miastenia

64
Q

Anti-Mielina

A

S. Guillain Barré

65
Q

Ac Anti Gangliósidos

A

S. Guillain Barré

66
Q

Anti-Descarboxilase do Ác. Glutâmico 67 (GAD67)

A

Síndrome de Stiff-man

67
Q

Anticorpos dos Síndromes Paraneoplásicos cerebelosos

A

Anti-Neurónios
Anti-células de Purkinje
Anfisina
CV2

68
Q

Ac Anti-Fosfatase da tirosina (IA2)

A

DM I

69
Q

Anti-7-2RNP

A

Esclerodermia Sistémica Progressiva

70
Q

Anti-Jo

A

Poliomiosite

Dermatomiosite

71
Q

Anti-Sp100

A

Cirrose Biliar Primária

72
Q

Anti-Histonas

A

Lúpus Eritematoso Medicamentoso

73
Q

Anticorpos típicos do Lúpus Medicamentoso

A

ANA

AntiHistonas

74
Q

Anticorpos típicos do S. Sjögren

A

ANA
Anti-SSA/SSB
Factor reumatóide

75
Q

Anticorpos mais importantes da Esclerodermia Sistémica Progressiva

A

Anti-Scl70
Anti-Fibrilharina
Anti-RNP

76
Q

Se suspeito de CREST, o que pesquiso?

A

Ac Anti-Centrómero

77
Q

Ac-Anti-Músculo Liso (ASMA) é sugestivo de…

A

Hepatite autoimune I

78
Q

Ac Anti-Antigénio Solúvel do Fígado (SLA/LP)

A

Hepatite Autoimune I

79
Q

Na suspeita de gastrite autoimune, pesquisar…

A

Anti-Células Parietais

80
Q

Na suspeita de anemia perniciosa, pesquisar…

A

Anti-Factor Intrínseco

81
Q

Na suspeita de Colangite Esclerosante Primária, pesquisar

A

Ac Anti-NANA

82
Q

Na suspeita de Doença Celíaca, pesquisar…

A

Anti-Transglutaminase (++)
Anti-Endomísio (++)
Anti-Gliadina
Anti-Reticulina

83
Q

Na suspeita de Doença Mista do Tecido Conjuntivo, pesquisar…

A

ANA

Anti-RNP

84
Q

Anticorpos de Hepatite Auto-Imune II

A

Anti-LKM 1

Anti-LC-1

85
Q

Na doença de Crohn, que anticorpos é que podemos encontrar?

A

Ac Anti-Saccharomyces Cervisae (ASCA)

Ac Anti-Pâncreas exócrino

86
Q

Na suspeita de colite ulcerosa, que anticorpos podem estar presentes?

A

Anti-pANCA

Anti-Células de Goblet

87
Q

Anticorpo típico de Graves

A

TRABs

88
Q

Se suspeitamos de Goodpasteur, pesquisar…

A

Ac Membrana Basal Glomerular

89
Q

Anticorpos mais importantes numa Hepatite Autoimune I

A

Anti-Fibras de actina

Anti-Antigénio Solúvel do Fígado

90
Q

Na doença de Wegener podemos ter…

A

Anti-cANCA tipo Antiproteinase 3 (PR3)

91
Q

Na Poliangeite Microscópica, podemos ter…

A

Anti-pANCA tipo Mieloperoxidase (MPO)

92
Q

Na suspeita de pênfigo, pesquisar…

A

Anti-Substância Intercelular

93
Q

Na suspeita de pênfigo bulhoso, pesquisar…

A

Ac-Anti-Membrana basal epidérmica

94
Q

Na suspeita de Lúpus cutâneo subagudo, pesquisar…

A

Anti-SSA

95
Q

Na suspeita de Addison, pesquisar

A

Ac Anti-21-hidroxilase

96
Q

Na suspeita de Miastenia, pesquisar…

A

Ac. Anti-Receptores da Ach

Ac. Anti-Músculo Estriado

97
Q

Na suspeita de Eaton-Lambert, pesquisar…

A

Ac Anti-Canais de Cálcio

98
Q

Na suspeita de Stiff-man, pesquisar…

A

GAD67 (Ac Anti-Descarboxilase do glutamato 67)

99
Q

Na suspeita de Guillain-Barré, pesquisar…

A

Anti-Mielina, MAG, Gangliósidos.

Imunologia (33 decks)

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