Pathoma: Restrictive Diseases Flashcards

1
Q

What cytokine induces fibrosis (excessive repair) in the lungs?

A

TGF-ß

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2
Q

Some medical treatments can cause interstitial fibrosis. Name two medications and one therapy.

A

Bleomycin and neomycin

Radiation therapy

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3
Q

Symptoms of idiopathic pulmonary fibrosis include __________.

A

progressive dyspnea and cough

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4
Q

Within alveolar macrophages, silicate impairs ___________.

A

phagolysosome formation; this results in increased risk of TB

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5
Q

Sarcoidosis can also affect the _________, mimicking Sjögren’s syndrome.

A

salivary and lacrimal glands

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6
Q

Noncaseating granulomas raise serum __________.

A

calcium

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7
Q

________ also presents with granulomas.

A

Hypersensitivity pneumonitis

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8
Q

Symptoms of hypersensitivity pneumonitis usually resolve with __________.

A

removal of the causative exposure

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