Pathoma: Inflammatory Dermatoses

Question 1

In the skin, the basement membrane separates the ___________.

Answer 1

epidermis from the dermis

Question 2

“Keratinocytes” includes __________.

Answer 2

the stratum basalis, stratum spinosum, stratum granulosum, and stratum corneum

Question 3

The stem cells of the skin are found in the ________.

Answer 3

stratum basalis

Question 4

All of the adnexal structures of the skin are found in the ___________.

Answer 4

dermis

Question 5

Cells in the stratum corneum are ___________.

Answer 5

anucleate

Question 6

Atopic dermatitis is characterized by ___________.

Answer 6

pruritis, erythema, oozing, vesicles; often on the face and flexor areas; type I immunopathology

Question 7

Contact dermatitis has all of the characteristics of atopic dermatitis, except __________.

Answer 7

contact dermatitis is a type IV immune response (frequently to nickel, poison ivy, detergents)

Question 8

Describe the pathology acne.

Answer 8

Increased sebum production leads to blocking of the pore; blocking of the pore leads to P. acnes infection; P. acnes leads to lipase production, which breaks down fatty acids, themselves proinflammatory

Question 9

Psoriasis usually occurs on the __________.

Answer 9

extensor surfaces, scalp, and nails

Question 10

Histologically, psoriasis leads to _________.

Answer 10

elongated dermal papillae (source of pinpoint bleeding, called “Auspitz” sign) and thickened epidermis

Question 11

Phototherapy is __________.

Answer 11

UVA

Question 12

Lichen planus is associated with ________.

Answer 12

(all the P’s) pruritic, planar (flat on its surface, even though it’s raised), polygonal, purple papules; commonly on wrists and oral mucosa

Question 13

Which hepatitis is lichen planus associated with?

Answer 13

HCV