Pathoma: Nephritic Syndrome

Question 1

List the four big signs of nephritic syndrome.

Answer 1

Edema
Hypertension
Oliguria
Glomerular bleeding (as indicated by casts)

Question 2

Subepithelial humps are indicative of which nephritic syndrome?

Answer 2

Post-infectious glomerulonephritis

Question 3

In crescentic disorders, what are the crescents made of?

Answer 3

Macrophages and fibrin

Question 4

What is the most common type of nephritic renal disease that you see in lupus?

Answer 4

Diffuse proliferative glomerulonephritis with sub-endothelial deposits (this is nephritic). Membranous nephropathy occurs, too, but that is nephrotic.

Question 5

If a patient tests positive for p-ANCA, what two disorders might they have?

Answer 5

Microscopic polyangiitis

Churg-Strauss

Question 6

Alport syndrome leads to ___________ of the basement membrane.

Answer 6

thinning and splitting