Onco - Lung Bk Immunohisto Flashcards
1
Q
markers to verify neuroendocrine differentiation witihn a tumor: tumor markers include
A
NSE CD56 NCAM synaptophysin chromogranin Leu7
2
Q
TTF-1
A
thyroid
pulmonary adenocarcinoma
3
Q
a negative TTF-1 excludes the possibility of a lung primary. T/F
A
F as it may be + in extrapulmonary neuroendocrine tumors
4
Q
an aspartic protease that plays an important role in maturation of surfactant B7 and is expressed in cytoplasm of type II pneumocytes
A
Napsin A
5
Q
Nap A + TTF-1 +
A
primary lung adenocarcinoma
6
Q
Nap A (-) TTF-1 (-)
A
primary lung squamous cell carcinoma
7
Q
Nap A (-) TTF-1 (+)
A
primary SCLC
8
Q
CK7 (+) CK20(-)
A
mesothelioma
9
Q
CK7 (-) CK20(-)
A
squamous cell lung CA
10
Q
useful marker for detection of NSCLCs with squamour differentiation
A
p63
