IDS Fungal Candidiasis Flashcards

1
Q

characteristic of oral candidiasis

A

painless
creamy white plaque-like lesions of the buccal or oropharyngeal mucosa or tongue surface

easily scraped

angular cheilosis

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2
Q

Characteristics of esophageal candidiasis

A

retrosternal burning pain or discomfort
odynophagia
endoscopic examination reveals creamy white plaque-like lesions of the esophagus

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3
Q

Characerstics of candida vulvovaginitis

A

white adherent vaginal discharge
thin whitish curds
pain burning and itching

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4
Q

T/F occurrence of oropharyngeal and esophgeal candidiasis is an indicator of immune suppression

A

T

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5
Q

CD4 level susceptible to candidiasis

A

CD4 <200cells/uL

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6
Q

T/F reccurrent vulvovaginal candidiasis should be considered a sentinel of HIV infection

A

F; alone, it should not be considered sentinel of HIV infection

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7
Q

Sequelae of hematogenous dissemination of candida

A

microabscess and small macroabscess in major organs

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8
Q

Which Candida species is not susceptible to azoles and AmB

A

C. krusei

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9
Q

C. glabrata is least susceptible to which class of antifungal?

A

azoles

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10
Q

Which Candida species is susceptible to all antifungals?

A

C. guiliermondii

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11
Q

C. albicans treatment: which is most effective among the ff

a. fluconazile
b. itraconazole
c. voriconazole
d. AmB

A

A

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12
Q

C. albicans tx. which is most effective among the ff

a. Caspofungin
b. itraconazole
c. AmB
d. voriconazole

A

A; for C. albicans, more effective tx:
fluconazole
echinocandins
AmB

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13
Q

Treatment for oropharyngeal candida

A

fluconazole PO OD 7-14 days

check ppt for alternatives

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14
Q

Treatment for esophageal candidiasis

A

fluconazole 100mg IV/PO OD for 14-21 days

check ppt for alternative

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15
Q

Uncomplicated vulvovaginal candidiasis tx

A

fluconazole PO 150 mg 1 dose

topical azoles for 3-5 days

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16
Q

Fluconazole refractory oropharyngeal and esophageal candidiasis

A

itraconazole soln >200mg PO

check for alternatives

17
Q

Severe recurrent vulvovaginal candidiasis tx

A

fluconazole 150 mg q 72H 2-3 doses

18
Q

Disseminated candidiasis

A

AmB IV 0.5-1mkd, or lipid formulation