Fever and Rash - CDME Clinical Syndromes

Question 1

Headache, weakness,
malaise, myalgias, neuroinvasive
disease (encephalitis,
meningitis, flaccid
paralysis

Answer 1

West Nile Fever

Question 2

Hemolymphatic disease
followed by meningoencephalitis;
Winterbottom’s
sign (posterior cervical
lymphadenopathy) (T. brucei
gambiense)

Answer 2

African

trypanosomiasis

Question 3

Arthritis; cardiac, pulmonary,
renal, hematologic,
and vasculitic disease

Answer 3

Systemic lupus

erythematosus (SLE)

Question 4

Recurrent fever, headache,

myalgias, hepatosplenomegaly

Answer 4

Relapsing fever

Question 5

Headache, musculoskeletal
pain (“breakbone
fever”); leukopenia; occasionally
biphasic (“saddleback”)
fever

Answer 5

Dengue fever

Question 6

Compared with Lyme
disease: fewer constitutional
symptoms, tick bite
more likely to be recalled;
other Lyme disease
sequelae lacking

Answer 6

Compared with Lyme
disease: fewer constitutional
symptoms, tick bite
more likely to be recalled;
other Lyme disease
sequelae lacking

Question 7

Myalgias; aseptic meningitis;
fulminant form: icterohemorrhagic
fever (Weil’s
disease)

Answer 7

Leptospirosis

Question 8

Headache, myalgias,

leukopenia

Answer 8

Human monocytotropic

ehrlichiosisc

Question 9

Headache, myalgias, chills,
photophobia occurring
acutely; CNS disease, myocardial
disease, arthritis
weeks to months later in
some cases

Answer 9

Lyme disease

Question 10

Variable abdominal pain
and diarrhea; headache,
myalgias,

Answer 10

Typhoid fever

Question 11

Regional adenopathy;
recurrent fevers if
untreated

Answer 11

Rat-bite fever (sodoku)