NSAID Flashcards

1
Q

COX-2 selectivity - very selective ?

A

etori-coxib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

COX-2 moderately sslective ?

A
  1. rofe-coxib
  2. cele-coxib
  3. etodolac
  4. meloxicam
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

COX-2 weakly selective ?

A
  1. diclofenac
  2. sulindac
  3. piroxicam

D-S-P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Most potent NSAID ?

A

KETOROLAC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which NSAID in BD ?

A

etoricoxib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

salicylates - NSAID ?

According to chemical nature & structure

A
  1. aspirine
  2. sulfasalazine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

propionic acid derivatives ?

A
  1. ibu-feno-keto=PROFEN
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

acetic acid derivative name ?

A

1indomethacin
etodolac
sulindac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

fenamic acid derivatives NSAID ?

A
  1. mefenamic acid
  2. tolfenamic acid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

enolic acid derivatives ?

A

piro-teno-melo-XICAM !!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CVS safe NSAID ?

A

naproxen q

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Commonly used NSAID ?

A
  1. diclofenac
  2. aspirin
  3. aceclofenac
  4. ketorolac
  5. etoricoxib
  6. ibuprofen
  7. naproxen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Indications of Aspirin/NSAID ?

A

Anti
inflmmatory-pyretic-platelet-analgesic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

renal safe NSAID ?

A

sulindac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

children safe NSAID ?

A

ibuprofen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

which NSAID is Bronchial astham safe ?

A

ibuprofen
+
naproxen
+ COX-II inhibitors

7.4.2025
11.23PM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

which NSAID used as post-operative & inj ?

A

ketorolac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

which NSAID is 🤰 safe ?

A

paracetamol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

antidote of paracetamol ?

A
  1. N-acetylcystine
  2. methionine

728

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

overdose of paracetamol A/E ?

A
  1. Hepatotoxicity
  2. renal necrosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Contraindications of NSAID ?

A
  1. active bledding peptic ulcer
  2. Chronic PUD
  3. CLD
  4. bronchial asthma
  5. gout
  6. bleeding disorder
  7. imediatly after burn - diye dile -Curling ulcer
  8. swine flu & influenza
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

why NSAID/Aspirin is not given in a viral infected child >??

A

reyes syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

commonly used analgesics?

A
  1. paracetamol
  2. aspirin
  3. diclofenac
  4. mefenamic acid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

which NSAID is used as analgesic in postoperative pain management?

A
  1. diclofenac
  2. ketorolac
24
what is Reyes syndrome ?
swelling in the liver and brain
25
which NSAID IN primary dysmenorrhea ?
mefenamic acid
25
which NSAID is used as tocolytics ?
* indomethacin * sulindac
26
indicatttions of NSAID ??
* AnalgesicAnalgesics * anti-inflammatory-antipyretics - antiplatelet * tocolytics * patency of ductus arteriosus * primary dysmenorhhe
27
which NSAID used in patency of ductus arteriosus ?
indomethacin >
28
which NSAID used in Gout ?
indomethacin
29
risk of paracetamol in 🤰?
3rd trimester - risk of premature closure of the ductus arteriosus
30
less CVS effect of which NSAID ?>
* celecoxib * naproxen
31
which COX-2 inhibitor are not in market ? reason >>
1. rofecoxib 2. valdecoxib 3. due to their increasing CVS risk
32
recent status of COX-2 ?
not in market !!!!
33
why COXIB >>> NSAID ?
1. no GIT bleeding 2. donot precipiatet Brionchail asthma 3. donot cause gastric mucosal damage | 732
34
what if - ibuprofen is taken regularly ??
cardio-protective action of aspirin may block
35
which NSAID act on both brain & periphery ?
1. ibuprofen 2. aspirin 3. ketoprofen 4. diclofenac
36
overdose of aspirin effect ?
NaOH er maddhome Ph of urine alter - urine alkalization
37
A/E of NSAID ?? | GIT sobar age bolte hobe
1. ab pain 2. peptic ulcer 3. dyspapsia 4. ulceration 5. bleeding
38
Other A/E of NSAID "?
CNS= headache + tinnitus+ dizziness respiratory = bronchospasm CVS=fluid retemtion + HTN + edema hypersensitivity neutropenia + thrombocytopenia
39
why bronchospasm by NSAID >?
by reducing bronchodilator Prostaglandin synthesis thats why NSAID aggravate Bronchail asthma
40
why aspirin is stopped one week before surgery ?
720
41
antiplatelet effect of aspirin ?
720 page
42
analgesic effect of NSAID ?
719 PAGE
43
Anti-pyretic effects of NSAID /
722 page
44
anti-inflammatory effect of NSAID ??
721 PAGE
45
NSAID + warferin ?
risk of bleeding
46
nsaid + fluroquinolone ?
risk of convulsion
47
nsaid + sulfonylurease ? oral hypoflycemic agents = ??
inc action & duration
48
nsaid + ACEi /ARB = ?
1. RENAL impairment \ 2. hyperkalemia
49
nsaid + diuretics = ?
dec effects of diuretics
50
contraindications of COX-i ?
* IHD * HTN * CVD * Cardiac failure | 733
51
analagesic effect excellent /
ketorolac
52
aspirin dose /
75-150 mg per day
53
anti-inflammatory drugs name /
* steroidal = cortisone + hydrocortisone * non-steroidal = Acetaminophen + aspirin
54
Paracetamol kivabe NSAID <>
Headache Fever
55
Yaba kemne ase ?
amphetamaine with caffeine
56
what drug should be prescribe along side of NSAID medication ?
PPI H2 receptor blocker Misoprostol 13.4.2025
57
indication of NSAID ? one must >
acute gouty arthritis