Anti-Amoebic Drugs

Question 1

Luminal amoebicides in large gut names ??

Answer 1

1. iodoquinol
   paromomycin

Question 2

systemic / mixed amoebicides name ??

Answer 2

• chloroquine
  de-hydro-emetine

Question 3

Mixed amoebicides name ??

Answer 3

• metronidazole
  ti-nidazole
  sec-nidazole
  omidazole

849

Question 4

Hepatic amoebiasis / amoebic liver abscess Tx ??

Answer 4

Metronidazole - 800 mg 8 hourly for 5 days
/
Tinidazole - 2gm daily for 3 days

850

Question 5

Surgical Tx for Hepatic amoebiasis ??

Answer 5

Aspiration
850

Question 6

M/A of Metronidazole??

Answer 6

850

Question 7

selective toxicity of M ??

Answer 7

Only against Anaerobic bacteria

850

Question 8

Indications / Uses of Metronidazole??

Answer 8

1. Trichomoniasis
   Giardiaisis
   acute & chronic amoebic dysentry
   amoebic liver abscess
   PUD
   Inta Ab septicemia
   Tetanus
   Pseudomembranous colitis
   Diabetic gangrene
   aspiration pneumonia

851

Question 9

A/E of metronidazole??

Answer 9

1. metallic taste
   dry mouth
   N-V-D
   Headache
   dizziness
   insomnia
   vertigo
   disulfiram likee effect

Question 10

Contraindication of M ??

Answer 10

Pregnant & lactating women
young children
liver insufficiency

Question 11

why metallic taste in M ??

Answer 11

nitro group = that interact with taste receptor = bitter/metallic sensation

852

Question 12

drugs name that produce metallic taste ??

Answer 12

M
tetracycline
rifampicin
pentamidine isothionate

Question 13

Disulfiiram like effects drugs name ??

Answer 13

M
Cefotetan
trimethoprim

Question 14

Disulfiram like effect ??

Answer 14

N-V can occur if alcohol is ingested during theerapy

852

Question 15

Giardiasis Tx ??

Answer 15

M = 400 mg 8 hoursly for 10 days

852

Question 16

Tx of intestinal amoebiasis ??

Answer 16

M- 800 mg 8 hourly for 5days
/
Diloxanide furoate - 500 mg 8 hourly for 10 days