Anti-HTN drugs

Question 1

cardio selective CCB ??

Answer 1

• Verapamil
  diltiazem

362

Question 2

vessel selective CCB ??

Answer 2

1. Amlodipine
   nicardipine
   nimodipine
   nifedipine

362

Question 3

M/A of cardioselective CCB ??

Answer 3

363

Question 4

M/A of vessel selective CCB ??

Answer 4

363

Question 5

A/E of CCB??

Answer 5

• Ankle edema
  flushing
  izziness
  headache
  reflex tachycardia
  constipation

Question 6

why pedal edema by CCB ??

Answer 6

1. rise in intracapillary pressure - as a result of selective dialtion by CCB of the precapillary arterioles
2. inc capillary permeability
3. expulsion of fluid in tissue

365

Question 7

indications of CCB ??

Answer 7

• HTN
  IHD
  Cardiac arryhtmia
  hypertrophic cardiomayopathy
  subarachnoid hemorrhage
  PVD
  Preganancy + HTN
  esophageal spasm
  achalasia

364

Question 8

which CCB does not cause ankle edema ??

Answer 8

CLINIDIPIN

364

Question 9

Pregnancy safe CCB ??

Answer 9

Nifedipine

366

Question 10

pregnancy safe AntiHTN drugs name ??

350

Answer 10

• alpha methyl dopa
  nifedipine
  hydralazine
  labetalol
  atenolol

Question 11

HTN + DM = ??

Answer 11

• D
  ACEi
  ARB
  CCB

Question 12

HTN + Bronchail astham ??

Answer 12

• CCB
  ARB
  D

Question 13

HTN + Chronic renal disease ??

`

Answer 13

ACEi
ARB

351

Question 14

Why not ACEi in HTN + BA ?

Answer 14

ACEi= bradykinin - dry cough

Question 15

recently in pregnancy which anti-htn ??

Answer 15

labetalol

Question 16

labetalol timeline ??

Answer 16

3rd trimester

350

Question 17

Role of ACEi ??

Answer 17

355

Question 18

indications of ACEi ??

Answer 18

1. MI
   HTN
   Post MI
   DN
   Cardiac hypertrophy
   chronic HF

354

Question 19

role of ACEI in DM + HTN ??

Answer 19

• Prevent progression of renal disease
  decrease albuminuria
  decrease retinopathy

355

Question 20

A/E of ACEi ??

Answer 20

1. dry cough
   angioedema
   first dose hypotension
   hyperkalemia
   acute rernal failure
   skin rash
   teratogenesity

356

Question 21

AAlpha methyl dopa M/A ?

372

Answer 21

373

Question 21

contraindications of CCB ??

Answer 21

HF

Question 22

can we give after delivery ??

Answer 22

no - CNS depression - suicidal tendency

372

Question 23

AMD in men ??

Answer 23

NO
Endocrine dysfunction

Question 24

AMD indication ??

Answer 24

HTN + Pregnancy

Question 25

A/E of AMD ??

Answer 25

• hypotension
  nightmares
  + coombs test
  hemolytic anemia
  hepatitis
  depression
  vertigo

Question 26

ACEi + Loop D = ??

i

Answer 26

ACEi - Hyperkalemia
LD - Hypokalemia

Question 27

ACEi + spironolactone = ??

Answer 27

more hyperkalaemia

Question 28

ACEi + NSAID = ??

Answer 28

aspirine - block bradykinin mediated vasodilation
sso ACEi - anti-HTN effect loss

357 m

Question 29

ACEi contraindications ??

Answer 29

• RF
  Hyperkalemia
  BA
  Bilateral renala rtery stenosis
  preganancy

357

Question 30

direct renin in hibitos name ??

Answer 30

aliskerin

361

Question 31

Why ARB&raquo_space;» ACEi ??

Answer 31

1. no DRY cough
   lower - angioedema
   lower - rashes

Question 32

ARB names ??

Answer 32

• los-Val-telmi-oleme - SARTAN

Question 33

ACEi name ??

Answer 33

• Capto-Enala-Lisino-Rami-Moexi-Quina-Rami-PRIL

353

Question 34

Renin release inhibiutos name ??

Answer 34

Beta bl;oclers name 353

Question 35

aldosterone antagonists anme ??

Answer 35

spironolactone
eplerenone

353