Laxatives - GI Pharma Flashcards
1
Q
Bulk forming laxatives ??
A
- Ispaghula husk
- Bran
- Psyllium
- Methylcellulose
- Polycarbophil - Synthetic fibers
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2
Q
Osmotic laxatives name ??
A
- Mg Hydroxide
- Mg Citrate
- Na Phosphate
- Sorbitol
- Lactulose
- Polyethylene Glycol- PEG
546
3
Q
Stool softeners ??
A
- Docusate
- Liquid paraffin /Mineral oil
- Glycerin suppository
546
4
Q
Stimulant laxatives / Cathartics name ??
A
- Senna
- Aloe
- Bisacodyl
- Cascara
547
5
Q
Chloride channel activator name ??
A
1.LubiProstone
2.LinaClotide
3.PleCanatide
6
Q
Serotonin 5HT4 receptor agonists name. ?
A
1.Tegaserod
2.CisaPride
3.PruCaloPride
7
Q
Pro kinetic agents ??
A
1.Serotonin 5HT4 receptor agonists
2.Ophoid receptor antagonists
3.Misoprostol
8
Q
Non pharmacological approach of constipation ??
A
- Fiber rich diet = (20-30) g/day
- Adequite fluid intake
- Regular exercise
- The heedinf of natures call
- Avoid constipating drugs
547
9
Q
A/E of bulk forming laxatives ??
A
- Flatus
- Ab bloating
548
10
Q
Indications of lactulose ??
A
- Constipation
- Hepatic encephalopathy
- Diagnostic procedure-Colonoscopy/surgery
548
11
Q
Contraindications of Bulk forming laxatives ??
A
- Megacolon
- Megarectum
- Intestinal obstruction
- Fecal impaction should be treated before fibre supplementation
548
12
Q
A/E of lactulose ??
A
- Hypermagnesemia
- Severe flatus
- Cramps
- IV volume depletion
- Electrolyte fluctuations
548
13
Q
Contraindications of lactulose ??
A
- Renal F
- Severe cardiac disease
548
14
Q
Stimulant laxatives/Bisacodyl mechanism ??
A
- direct stimulation of the ENS
- inc colonic electrolyte & fluid secretion by irritation
549
15
Q
Indications of SL/Bisacodyl ??
A
- Constipation
2.Long term tx of consstipation
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