Cholinergic Pharmacology Flashcards

1
Q

what is cholinergic neuron ?

A

neurons that secrete acetylcholine

200

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2
Q

excitatory NT ?

A
  • epinephrine
  • glutamate

GE

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3
Q

inhibitory NT ?

A
  • s
  • dopamine
  • GABA
  • serotonin
  • glycin
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4
Q

Cholinergic receptors name ?

A
  1. Muscarinic
  2. nicotinic
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5
Q

both inhibitory + inhibitory NT ?

A
  • h
  • prostaglandin
  • 5HT
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6
Q

M1 location

neural

A
  • CNS neurons
  • sympathetic postganglionic neuron
  • presynaptic sites
  • parietal cells
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7
Q

M1 function ?

A
  • cns excitaion
  • gastric secretion
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8
Q

M2 site ?

A
  1. myocardium
  2. smooth muscle
  3. presynaptic site
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9
Q

M2 function ?

A
  1. cardiac & neural inhibtion
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10
Q

M3 site ?

glandular

A
  • exocrine gland
  • smooth muscle
  • endothelium
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11
Q

M3 funtion ?

A
  • inc gastric & salibvary secretion
  • GIT muscle contraction
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12
Q

M4 site ?

neural inhibition

A
  • CNS neuron
  • vagal nerve ending
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13
Q

M5 site ?

neural excitation

A
  • CNS neuron
  • endothelium
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14
Q

Nicotinic Nn ?

A
  • CNS
  • Adrenal medulla
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15
Q

Nicotinic Nm ?

A
  1. skeletal muscle
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16
Q

directly Acting cholinester ?

A
  1. Ach
  2. methacholine
  3. carbachol
  4. bethanechol
17
Q

directly alkaloids ? name ??

A
  1. N
  2. M
  3. lobeline
  4. pilocarpine
18
Q

indirectly irreversible drug name ?

A
  • malathion
  • parathion
  • echothiophate
  • diazinion
19
Q

indirectly - reversible ?

A
  • physos-neos-pyridos-dis-rivas-TIGMINE
20
Q
A
21
Q
A
22
Q
A
23
Q
A
24
Q
A