Cell Wall synthesis inhibitors Flashcards

1
Q

Cell wall sy thesis inhibitors name ?

A
  • penicillin
  • cephalosporin
  • cycloserine
  • bacitracin
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2
Q

natural P ?

A
  1. benzylP /P-G
  2. phenoxyMethylP /P-V
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3
Q

Semi synthetic P ?

A
  1. Amoxicillin
  2. ampicillin
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4
Q

narrow spectrum P /

A

P-G & P-V

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5
Q

Broad spectrum P ?

A

A+A

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6
Q

beta lactamase sensitive ?

A
  1. A
  2. A
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7
Q

Beta lactamase resistant P ?

A
  1. cloxacillin
  2. Di-cloxacillin
  3. flu-cloxacillin
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8
Q

indication of P-G ?

A
  • sub acute bacterial endocarditis
  • syphillis
  • streptococcal infections
  • gonorrhoea
  • gas gangrene
  • tetanus
  • pneumococcal
  • prophylactic use

SGPT- 3221

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9
Q

indication of P-V ?

A
  • streptococcal
  • pneumococcal
  • trench mouth
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10
Q

indications of ampicillin ??

A
  • SABE
  • shigellosis
  • gonorrhea
  • RTI
  • neonatal infections
  • acute cholecytitis
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11
Q

indications of amoxicillin ?

A
  • UTI
  • gonorrhoea
  • child infections
  • stretococcal infections
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12
Q

M/A of P ?

A

page-758

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13
Q

benzathine P is preferred for prophylaxis of RF ??

A
  1. reduce the risk of subsequent acute RF
  2. NO resistance
  3. once monthly dosing
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14
Q

anti-microbials used in P hypersensitivity?

A
  • macrolides
  • metronidazole
  • vancomycin
  • aztreonam
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15
Q
A
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16
Q
A
17
Q
A
18
Q
A
19
Q
A
20
Q

anti-staphylococcal p ?

A
  • cloxacillin
  • o-cloxacillin
  • flu-cloxacillin
  • nafcillin
  • oxacillin
21
Q

non-beta lactam bacterial cell wall synthesis inhibitors name ??

A
  • vancomycin
  • cycloserine
  • bacitracine
  • daptomycin
  • Dalba-Tela-Orita-VANCIN
22
Q

Beta lactamase inhibitors >

A

calvulanic acid
sul-bactam
tazo-bactam
avi-bactam
rele-bactam

23
Q

amoxicillin + calvulinic acid = ?????

A

a= destroy by beta-lactamase
but CA inhibit it
so A is prolonged

24
Q

M/A of cephalosporine ?

A

same as P

25
Q

4th genetgeneration C ?

A

Cefepime

26
Q

3rd generation C /

A
  • cefixime
  • ceftriaxone
  • ceftazidime
  • cefotaxime
27
Q

1st G c ?

A

cephradine
cefa-droxil
cefa-zolin

28
Q

2nd G C ?

A

Cefuroxime
cefotetan
cefoxitin
cefaclor

29
Q

A/E of P ?

A
  • HYpersensitivy
  • seizure
  • \N-V-D
  • neutropenia
  • intestinal nephristis
  • hepatitis