Anti-Depressant Drugs

Question 1

pathophysiology of depression ?

Answer 1

1. neurotropic hypothesis
2. mono amine hypothesis

Question 2

neurotropic hypothesis of depression ?

Answer 2

brain derived neurotropic factor BDNF & endocrije factor === Loss

Question 3

SSRI name ?

Answer 3

1. fluo-xetine
2. paro-xetine
3. citalopram
4. sertraline

Question 3

MOno amine hypothesis ?

Answer 3

1. serotonin
2. nor-epinephrine
3. dopamine
4. DEFICIENCY

Question 4

SSNRI ?

Answer 4

1. venlafaxine
2. des-venlafaxine
3. duloxetine

Question 5

TCA name ?

Answer 5

1. ami-imi-trimi-desi
   2.TRPTYLINE

Question 6

Chronic pain -which Anti-D ?

Answer 6

dulo-xetine

Question 7

M/A of TCA ?

Answer 7

1. block reuptake of amine NT
2. block muscarine receptor
3. block alpha-adrenergic receptors
4. block pre-synaptic alpha-2 receptors
5. block H1 receptors

Question 8

A/E of TCA ?

Answer 8

1. = relief of depression

Question 9

indication of TCA ?

Answer 9

1. depression
2. anxiety disorder
3. panic disorde
4. rgeneralized anxiety
5. social phobia
6. chronic pain
7. insomnia
8. enuresis

Question 10

other use of TCA ?
smoking cessation ?

Answer 10

bupropion

Question 11

enuresis nocterna ?

Answer 11

amitryptyline + imipramine

Question 12

premature ejaculation which anti-D ?

Answer 12

escitalopram

Question 13

attention deficient which anti-d ?

Answer 13

bupropion + atomoxetine

Question 14

stress incontinence ? which anti-D ?

Answer 14

DULOXETINE

Question 15

block alpha adrenergic receptors effect ?

Answer 15

1. postural hypotension
2. reflex tachycardia
3. ejaculatory failure
4. constipation

Question 16

block of pre-synaptic alpha-2 receptors A/E ?

Answer 16

1. Tremor
2. insomnia
3. tachycardia

TIT

Question 17

SSRI&raquo_space;» TCA ?

Answer 17

1. NO A/E effects
2. absorbed well
3. no 1st pass metabolism
4. long T1/2
5. less frquent dosing

Question 18

safe anti-D drugs for children ?

Answer 18

1. fluxetine
2. sertraline
3. fluvoxamine

Question 19

young male Anti-D name ?

Answer 19

1. SNRI

Question 19

Which Anti-D can be used in Loss of libido ?

Answer 19

escitalopram

Question 20

A/E of TCA ? Anti-muscarinic effect /

Answer 20

1. dry skin & mouth
2. urine retention
3. blurred vision
4. constipation
5. tachycardia

Question 21

must say indications of TCA ?

Answer 21

neuropathic pain

Question 22

drugs used in neuropathic pain ?

PROFFFFFFFFFFF

Answer 22

1. Gabapentin
2. Pregabalin
   carbamazapine
3. Amitriptyline
4. Duloxetine
5. Tramadol
6. Lidocaine Patches
   7.nortryptyline

12-2-2025
2.58 AM

Question 23

drugs used in trigeminal neuralgia proffffffffffffffff

Answer 23

1. Carbamazepine 2. Oxcarbazepine 3. Gabapentin 4. Pregabalin 5. Baclofen 6. Lamotrigine

Question 24

why TCA in pruritis ?

Answer 24

TCAs like **doxepin** are used in pruritus due to their **potent antihistamine (H1-blocking) activity**, **sedative effects**, and ability to modulate **serotonin and norepinephrine pathways**, which help reduce itch signaling and improve symptoms, especially in conditions like chronic urticaria and atopic dermatitis.

Question 25

A/E of escitalopram ?

Answer 25

Erectile dysfunction delayed EJACULATION

Question 26

A/E of SSRI used as indication ?

Answer 26

escitalopram

Question 27

SSRI er kon A/E use hoy as a indication ?

Answer 27

A/E of escitalopram - Deylayed ejaculation Indiaction - Premature ejaculation