Anti-Depressant Drugs Flashcards

1
Q

pathophysiology of depression ?

A
  1. neurotropic hypothesis
  2. mono amine hypothesis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

neurotropic hypothesis of depression ?

A

brain derived neurotropic factor BDNF & endocrije factor === Loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

SSRI name ?

A
  1. fluo-xetine
  2. paro-xetine
  3. citalopram
  4. sertraline
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

MOno amine hypothesis ?

A
  1. serotonin
  2. nor-epinephrine
  3. dopamine
  4. DEFICIENCY
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

SSNRI ?

A
  1. venlafaxine
  2. des-venlafaxine
  3. duloxetine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

TCA name ?

A
  1. ami-imi-trimi-desi
    2.TRPTYLINE
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Chronic pain -which Anti-D ?

A

dulo-xetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

M/A of TCA ?

A
  1. block reuptake of amine NT
  2. block muscarine receptor
  3. block alpha-adrenergic receptors
  4. block pre-synaptic alpha-2 receptors
  5. block H1 receptors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

A/E of TCA ?

A
  1. = relief of depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

indication of TCA ?

A
  1. depression
  2. anxiety disorder
  3. panic disorde
  4. rgeneralized anxiety
  5. social phobia
  6. chronic pain
  7. insomnia
  8. enuresis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

other use of TCA ?
smoking cessation ?

A

bupropion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

enuresis nocterna ?

A

amitryptyline + imipramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

premature ejaculation which anti-D ?

A

escitalopram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

attention deficient which anti-d ?

A

bupropion + atomoxetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

stress incontinence ? which anti-D ?

A

DULOXETINE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

block alpha adrenergic receptors name ?

A
  1. postural hypotension
  2. reflex tachycardia
  3. ejaculatory failure
  4. constipation
16
Q

block of pre-synaptic alpha-2 receptors A/E ?

A
  1. Tremor
  2. insomnia
  3. tachycardia

TIT

17
Q

SSRI&raquo_space;» TCA ?

A
  1. NO A/E effects
  2. absorbed well
  3. no 1st pass metabolism
  4. long T1/2
  5. less frquent dosing
18
Q

safe anti-D drugs for children ?

A
  1. fluxetine
  2. sertraline
  3. fluvoxamine
19
Q

young male Anti-D name ?

A
  1. SNRI
19
Q

Which Anti-D can be used in Loss of libido ?

A

escitalopram

20
Q

A/E of TCA ? Anti-muscarinic effect /

A
  1. dry skin & mouth
  2. urine retention
  3. blurred vision
  4. constipation
  5. tachycardia