Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pharmacology-PROF > Diarrhea & AntiDiarrheal Drugs > Flashcards

Diarrhea & AntiDiarrheal Drugs Flashcards

1
Q

Oral Rehydration Solution ???

A

Oral Rehydration Salt + Adequate water = ORS

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Different types of ORS ??`

A
  1. Citrate saline
  2. Bicarbonate saline
  3. Rice saline

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Trisodium Citrate Dihydrate in ORS ?

A

2.9gm/L

according to lecture slide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

NaCl in ORS ?/

A

2.6 gm/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

KCl in ORS ??

A

1.5 gm/L

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dehydration consequences?

A
  1. Shock
  2. Hypovolemia
  3. Renal failure

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Anhydrous glucose in ORS ?/

A

13.5gm/L

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Water of the ORS function ??

A

Corrects fluid loss
Dehydration

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

NaCl & KCl function ??

A
  1. Correct electrolyte loss
  2. Maintain electrolyte balance

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Citrate function of ORS >??

Trisodium Citrate dehydrate - 2.5gm/L

A
  1. inc absoprtion of Na+ & Glucose
  2. dec stool output

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

HCO3- Bicarbonate function ?/

A

Correct the acidosis

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Glucose function of ORS ??

A

Na+ absorption by Na+ Glucose Co-Transporter

559

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Opioid agonists name ??

AntiMotillity drugs name

A
  1. Codeine
  2. Loperamide
  3. Diphenoxylate

560

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A/E of antimotility drugs ??

A
  1. Sequestration of fluid in the intestine
  2. Shock without any diarrhea
  3. Toxic megacolon
  4. Abdominal distension
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Indiscriminate use of antimotility drugs ??

A
  1. Antimotility drugs reduce gastric motility - thats why used in diarrhea

560`

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Contraindication of antimotility drugs&raquo_space;??

A

Should not be used in young childrens and pts with severe colitis

560

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Criticize indiscriminate use of antimicrobials in acute diarrhea ??

A

D caused by Virus Toxins Drugs – NO need of antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Antibiotics in D when ??

A

Only if D is caused by Bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Indication of antibiotics ??

A
  1. Diagnosed case of cholera
  2. Dysentry
  3. Systemic manifestation of endotoxic shock
  4. Presence of fecal leukocytes (pus cells ) for more than 10/HPF

561

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Tx of infective diarrhea ??

A
  1. Correction of dehydration
  2. Correction of electrolyte balance
  3. Use appropriate antibiotics
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Shigella – D - Drugs of 1st choice ?

A

Quinolones

561

19
Q

E coli – D – Drugs ??

A
  1. Cephalosporin
  2. TMP-SMZ

561

20
Q

Complylobacter jejuni - D– Drugs ??

A
  1. Arithromycin
  2. Erythromycin

561

21
Q

v cholerae ?

A

tetracycline
ciprofloxacin

22
Shigella te P drugs ?
Ciprofloxacin
23
Anti-ulcernat drugs ?
531 sucralfate misoprostol colloidal bismuth compund s
24
PPI is taken before or after meal ?
before meal
25
why PPI before meal ?
block H/K atpase which are most active post-meal best absoprtion empty stomach - inc bioavailabilut
26
which PPI can be taken anytime >
dexlansoprazole dual release
27
misoprostol GI function ?
PUD
27
which H2 blocker still in use >
famotidine
28
other than PUD misoprostol function >
induction of labour faciliation of labour Tx of PPH Tx of PUD
29
Pregnancy safe H2 ?
ranitidine famotidine
29
preganancy te kon H1 antiemetic
cyclizine promethazine
30
systemic antacid name ?
CaCO3 ALOH3 MgOH3 Mg - trisilicate
31
A/E of antacids ?
metabolic alkalosis belching constipation osmotic disarrhea milk alkali syndorme renal insufficiency hypercalcemia
32
anti-emetic drug
551
33
cytoprotection which drugs ?
same as anti-ulcerant
34
Severe D te ki korba ?
IV cholera saline
35
Severe D te ORS diba na ???
NO pt cannot take that orally
36
NSAID induce ulcer which one >
PPI munni mam
37
which other drug cause ulcer /.
steroid
38
which drug is used in steroid-induced ulcer <
PPI misoprostol
39
steroids + NSAID == ??/
high risk prophylaxis with PPI
40
BD te ORS e H2O koto ?
500 C C 2 powa
41
WHO -ORS water ?
1L
42
how loperamide act on Diarrhea >
Loperamide acts primarily by binding to opioid receptors in the gastrointestinal tract, inhibiting the release of acetylcholine and prostaglandins. This reduces peristalsis and intestinal secretion, increasing intestinal transit time and allowing for greater absorption of water and electrolytes, thereby alleviating diarrhea. (Source: Katzung & Trevor's Pharmacology) inc colonic transit time inc fecal water absoprtion dec mass colonic movement ' loperamide have anti-secretory action againts cholera toxin
43
should we use loperamide in D <
yeah 560 not cross BBB no analgesic more potent no addiction
44
kader loepramide dibo ?
561
45
M/A of antacid ?
532
46
domeperidone vs metoclopramide
555
47
loperamide kader jonno contraindications?
pt with IBD as they may develop paralytic ileus toxic megacolon

Pharmacology-PROF (38 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions