Neurological Basis of Psychiatric Dysfunction

Question 1

What is the primary neurotransmitter of the dorsal raphe nucleus?

Answer 1

Serotonin

Question 2

For what brain structure is histamine the primary neurotransmitter?

Answer 2

Tuberomamillary nucleus

Question 3

From what amino acid is serotonin derived?

Answer 3

Tryptophan

Question 4

What monoamine neurotransmitter is most associated with chronic pain disorders and depression?

Answer 4

Norepinephrine

Question 5

What neurotransmitter is primarily in the locus coeruleus?

Answer 5

Norepinephrine

Question 6

From what amino acid is acetylcholine derived?

Answer 6

Serine

Question 7

What is the metabolite of norepinephrine?

Answer 7

MHPG

Question 8

From what amino acid is histamine derived?

Answer 8

Histidine

Question 9

What neurotransmitter is most often implicated in sleep disorders?

Answer 9

Histamine

Question 10

What is the neurotransmitter activity in patients with depression?

Answer 10

Decreased dopamine, serotonin, and norepinephrine

Question 11

What monoamine neurotransmitter is most associated with depression and other mood disorders?

Answer 11

Serotonin

Question 12

Typical antipsychotics generally target what neurotransmitter receptors?

Answer 12

Dopamine > Serotonin

Question 13

What is the metabolite of serotonin?

Answer 13

5-HIAA

Question 14

Dopamine is primarily an (excitatory/inhibitory) neurotransmitter.

Answer 14

Both excitatory and inhibitory depending upon the receptor

Question 15

What is the metabolite of dopamine?

Answer 15

HVA

Question 16

Atypical antipsychotics generally target what neurotransmitter receptors?

Answer 16

Dopamine < Serotonin

Question 17

Glutamate and GABA are the primary neurotransmitters. From what amino acids are they derived?

Answer 17

Both are derived from glutamine. GABA is derived from glutamate

Question 18

Phenylalanine derives what monoamine neurotransmitters?

Answer 18

Epinephrine, norepinephrine, dopamine

Question 19

What monoamine neurotransmitter is most often implicated in substance abuse disorders and schizophrenia?

Answer 19

Dopamine

Question 20

Dopamine is the primary neurotransmitter in what brain structure?

Answer 20

Ventral tegmental area & substantia nigra

Question 21

What is the primary neurotransmitter of the Basal Nucleus of Meynert?

Answer 21

Acetylcholine

Question 22

What is the neurotransmitter activity in patients with schizophrenia?

Answer 22

Increased dopamine and serotonin, with increased or decreased glutamate

Question 23

GABA and serotonin levels are decreased in people with anxiety disorders. What neurotransmitter level is increased?

Answer 23

Norepinephrine

Question 24

What is the primary neurotransmitter for the synaptic vesicles?

Answer 24

Glutamate & GABA

Question 25

What is the safest treatment option for a mood disorder in a pregnant woman?

Answer 25

Electroshock Therapy