Musculoskeletal System Flashcards
muscle
specific tissue w/i body that generates mechanical force in response to NS motor output; afferent message to brain to effect message that stimulates muscles for motor output
3 types of muscle in vert
skeletal, smooth, cardiac
skeletal muscle
responsible for movements of skeleton; muscles attached to bones via tendons; tough cords made of connective tissue
muscle fiber
long, cylindrical multinucleated cell; several cels fused together to create fiber in dev; T-tubules, sarcoplasmic reticulum, characterized by myofibrils
T-tubules
infoldings of pm
sarcoplasmic reticulum (SR)
specific ER in muscle fibers
myofibrils
long fiber w/i muscle fibers, run lenthwise; 2 types of filaments: thin and thick
thin filament
2 strands of actin; contractile protein w myosin binding sites; regulatory proteins: tropomyosin, troponin
thick filament
about 350 myosin contractile protein molecules; each w head (stick out from molecule) and tail (associate w each other, thickness)
actin + myosin
found in many cells but only highly organized in muscle cells; filament arrangement in muscle cells give “striped” appearance;; skeletal muscle = striated
sarcomere
basic unit of contraction w/i myofibrial; repeated unit of overlapping thin/thick filaments; lots of sarcomeres lined up end to end = myofibril = lots of muscle; made of z-lines and m-lines
z-lines
location where thin actin filaments are attached; join adjacent sarcomeres together @ their ends
m-lines
location of thick myosine filaments; anchored in middle
during muscle contraction
think actin + thick myosin filaments slide past one another need connections to each other: some old connections break, some new connections form; overall result = sarcomere gets shorter: distance btwn z lines going to shorten, length of filaments does not change only amnt of over changes
muscle fiber @ rest
trophomyosin covers myosin binding site along the thin actin filament
muscle contraction steps
see notebk/textbk
myosin head
low E: ATP attached, relaxed; high E: ATP hydrolyzed to ADP+Pi, wound up, cocked, contract
cardiac muscle
wallks of heart; striated; branched muscle fibers; different area of heart contract simultaneously via intercalated discas; juctions allow ions to pass btwn cells; APs move quickly; can conract on their own bc alway want heart beating; high permeable to Na+ ions lots of depolarization lots of sponataneous APs
smooth muscle
walls of DT, bladder, uterus, BVs; NOT attached to bones, striated NOT highly organized; no T-tubules + no well dev SR; less eff sys for delivering messages; slow, sustained long involuntary contraction
3 function of skeleton
support, protection, movement
hydrostatic skeleton
fluid-filled skeletons bc closed compartment doesn’t let fluid out, under pressure; peristalsis = movement via rhythmic muscle contraction; ex: soft bodied inverts, cnidarians, nematodas, annelids, hydra = 2 layers of antagonistic contractile cells (inner = cicular = thinner/taller, outer = longitudinal = shorten/widen)
exoskeleton
external; comprised of nonliving tissue; producted by epidermal cells; no growth; molting via ecdysis; ex: arthoropods w chitin exo skeleton for protection and transmitting force, moluscs w CaCO3 exoskeleton secreted by mantle give proteins