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Immunology Week 2 > Monocyte/Macrophage stages/jobs > Flashcards

Monocyte/Macrophage stages/jobs Flashcards

1
Q

Activation

A

activated by INF-gamma or bacteria or LPS

secrete TNF, IL-1, IL-6

TNF, IL-1, IL-6 can activate synthesis of acute phase proteins or amplify macrophage response

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2
Q

Chemotaxis, tissue inflammation

A

TNF-alpha and IL-1 involved

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3
Q

Phagocytosis, scavenger function, tissue repair

A

nothing here

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4
Q

IL-12 and IL-10 cytokines

A

produced by activated macs, regulate polarization of TH1/Th2 adaptive immune response

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Immunology Week 2 (34 decks)

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