Mast Cells Flashcards
1
Q
Common at sites in the body that are
A
exposed to the external environment
2
Q
MAst cells are found in close proximity to
A
blood vessels, where they can regulate permeability and effector cell recruitment
3
Q
they can modulate
A
behavior of local cell populations, and neighboring effector cells through the release of mediators
4
Q
Inflammatory mediators of Mast Cells include
A
Prostaglandins, leukotrienes, platelet activating factor, histamine, heparin, proteases, chronoitin sulfates TNF antimicrobial peptides cytokines chemokines angiogenic factors growth factors
5
Q
Soem roles of mast cells include
A
recruit/activate monocytes,macs
migration/activation of dendritic cells
recruit/activate T cells
recruit/activate neutrophils, basophils, eosinophils
phagocytosis and inflammatory activity
effects on epithelial cells, tight junction proteins
degradation of endogenous toxic mediators
degradation of snake venom components
