Chemokines

Question 1

Chemokines are

Answer 1

cell adhesion molecules that stimulate movement and regulate migration of leukocytes from the blood stream to tissues

Question 2

Chemokines are a family of

Answer 2

structurally homologous cytokines possessing two internal disulfide bonds

the name is a contraction of chemotactic cytokine

Question 3

CC or Beta chemokines

Answer 3

the two defining cysteine residues are adjacent

Question 4

CXC or alpha chemokines

Answer 4

resides are separated by one amino acid

Question 5

C chemokines

Answer 5

contains a single cysteine

Question 6

CX3C chemokine

Answer 6

two cysteines are separated by three amino acids

Question 7

CCL2

Answer 7

MCP-1 mixed leukocyte recruitment

Question 8

CCL19

Answer 8

MIP-3beta T cell and dendritic cell migration into parafollicular zones of lymph nodes

Question 9

CCL21

Answer 9

SLC

T cell and dendritic migration into parafollicular zones of lymph nodes

Question 10

CXCL8

Answer 10

IL-8

neutrophile recruitment

Question 11

CXCL10

Answer 11

IP-10

effector T cell recruitment

Question 12

CXCL12

Answer 12

SDF-1-alpha-beta

mixed leukocyte recruitment, HIV coreceptor

Question 13

CXCL13

Answer 13

BCA-1

B cell migration into follicles

T follicular helper cell migration into follicles