lilley ch 54 anemia drugs Flashcards
formation of new blood cells
hematopoiesis
where are RBCs made
bone marrow
immature RBCs
reticulocytes
type of anemia:
Vitamin B12 deficiency (failure of the stomach to produce
intrinsic factor which allows B12 to be absorbed in the
intestine)
pernicious anemia
2 types anemia
pernicious anemia
folic acid deficiency
erythropoiesis-stimulating drug
epoetin alfa
contraindications epoetin alfa (3)
- uncontrolled hypertension
- hemoglobin levels >10-11 g/dL
- head and neck cancers
adverse effects epoetin alfa (3)
- hypertension
- fever
- pruritis
sources iron (3)
- meats
- certain veggies
- grains
4 foods enhance iron absorption
- orange juice
- veal
- fish
- ascorbic acid
4 foods impairing iron absorption
- eggs
- corn
- beans
- cereal products containing phytates
most common cause of pediatric poisoning deaths
iron
adverse effects iron (2)
- N/V/D
- black, tarry stools
treatment of severe iron intoxication
chelation therapy with deferoxamine
med with largest amount of iron per gram of salt consumed
ferrous fumarate (femiron)
most frequently used oral iron
ferrous sulfate
2 meds parenteral iron
- iron dextran
- ferric gluconate
injectable iron med indicated for pts with chronic renal failure
iron sucrose
adverse effect iron sucrose
hypotension
test dose required for which parenteral iron med
iron dextran
who should take folic acid supplements and when
pregnant women to prevent neural tube defects
start taking before pregnancy
contraindications for ferrous salts (3)
- ulcerative colitis
- peptic ulcer disease
- liver disease
when should oral forms of iron be taken
between meals
what can oral forms of iron be taken with and what should they not be taken with
ok: juice
no: milk, antacids
