Lilley ch 20 and 21 (cholinergic and anti-cholinergic drugs)

Question 1

direct acting cholinergic drug:

-causes increased bladder and GI tract tone and motility

Answer 1

bethanechol

Question 2

contraindications for cholinergic drugs (7)

Answer 2

• GI/GU tract obstruction
• bradycardia
• heart defects
• hyperthyroidism
• epilepsy
• hypotension
• COPD

Question 3

side effects of cholinergic drugs

Answer 3

overstimulation of parasympathetic nervous system

Question 4

antidote to cholinergic drug overdose

Answer 4

atropine

Question 5

neurotransmitter responsible for the transmission of nerve impulses to effector cells in the parasympathetic nervous system

Answer 5

acetylcholine

Question 6

cholinergic drugs _________ acetylcholine

Answer 6

mediate

Question 7

anticholinergic drugs __________ acetylcholine

Answer 7

inhibit

Question 8

major sites of action of anticholinergic drugs

Answer 8

• heart
• respiratory tract
• GI tract
• urinary bladder
• eye
• exocrine glands

Question 9

two examples of anticholinergic drugs

Answer 9

oxybutynin (ditropan)

tolterodine (detrol)

Question 10

adverse effects of anticholinergic drugs (6)

Answer 10

• constipation
• tachycardia
• palpitations
• hallucinations
• urinary retention
• decreased sweating (hot dry skin)