lewis ch 40 - obesity Flashcards

1
Q

in what populations are obesity the highest (3)

A
  • in the south
  • black and hispanics
  • lower income and less educated
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2
Q

classification of obesity: excess caloric intake for body’s metabolic demands

A

primary obesity

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3
Q

classification of obesity: due to other preexisting health conditions

A

secondary obesity

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4
Q

what may cause secondary obesity (4)

A
  • chromosomal and genetic anomalies
  • metabolic problems
  • CNS lesions and disorders
  • drugs (corticosteroids, antipsychotics)
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5
Q

what hormones and peptides interact with the hypothalamus (5)

A
  • leptin (from adipocytes)
  • insulin (from pancreas)
  • ghrelin (from stomach)
  • peptide YY (from colon)
  • cholecystokinin (from small intestine)
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6
Q

enzyme that suppresses hunger and increases fat metabolism

A

leptin

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7
Q

enzyme that stimulates hunger and regulates it by inhibiting leptin

A

ghrelin

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8
Q

what can an increased production of adipokines lead to (3)

A
  • insulin resistance
  • dyslipidemia
  • hypertension
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9
Q

conditions associated with obesity that can improve with weight loss

A
  • hypertension
  • high cholesterol
  • sleep apnea
  • diabetes type 2
  • heart disease
  • gallbladder disease
  • osteoarthritis
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10
Q

what is the name for abdominal obesity

A

android obesity

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11
Q

what are android obesity patients are greater risk for developing (3)

A
  • increased LDLs
  • high triglycerides
  • decreased HDLs
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12
Q

what disease is obesity one of the most important preventable causes of

A

cancer

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13
Q

what two types of cancer are strongly related to obesity

A

breast cancer
endometrial cancer
(due to excess estrogen which is stored in fat cells)

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14
Q

4 ways to classify Body weight and obesity

A
  • body mass index (BMI)
  • waist circumference
  • waist to hip ratio (WHR)
  • body shape
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15
Q

what BMI is considered underweight

A

18.5 or less

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16
Q

what BMI range is considered normal

A

18.5-24.9

17
Q

what BMI range is considered overweight

A

25-29.9

18
Q

what BMI is considered obese

A

30 or greater

19
Q

what BMI is considered extremely obese

A

40 or greater

20
Q

people with visceral fat with android obesity are at increased risk for (2)

A

cardiovascular disease

metabolic syndrome

21
Q

what waist circumference is considered obese for men

A

40” +

22
Q

what waist circumference is considered obese for women

A

35” +

23
Q

what is the optimal waist to hip ratio

A

0.8

24
Q

two basic techniques in behavior modification that can be used to help treat obesity

A

self-monitoring

stimulus control

25
Q

class of drugs that can be used to suppress appetite and treat obesity

  • high abuse potential
  • not recommended or approved by FDA
A

amphetamines

26
Q
class of drugs that can be used to suppress appetite and treat obesity
-recommended only for short term (3 months or less)
A

nonamphetamines

27
Q

drug for treating obesity:

  • selective serotonin agonist
  • suppresses appetite and creates sense of satiety
  • side effects: headache, dizziness, fatigue, nausea, dry mouth, constipation
A

lorcaserin (belviq)

28
Q

drug for treating obesity:

  • blocks fat breakdown and absorption in small intestine
  • inhibits action of intestinal lipases resulting in undigested fat being excreted in feces
  • side effects: stool leakage, severe liver injury may occur
A

orlistat (Alli)

29
Q

what is the criteria for eligibility for bariatric surgery

A
  • BMI greater or equal to 40

- BMI greater or equal to 35 with other significant comorbidities

30
Q

significant comorbidities (4) that combined with a BMI of 35 or greater can qualify someone for bariatric surgery

A
  • hypertension
  • type 2 diabetes
  • heart failure
  • sleep apnea
31
Q

3 broad categories of bariatric surgeries

A
  • restrictive
  • malabsorptive
  • combination of restrictive and malabsorptive
32
Q

type of restrictive bariatric surgery:

-limits stomach size with inflatable band around fundus of stomach

A

adjustable gastric binding (AGB)

33
Q

type of malabsorptive bariatric surgery:

  • 75% of stomach is removed
  • nonreversible
  • results in elimination of ghrelin
A

sleeve gastrectomy

34
Q

type of combination of restrictive and malabsorptive bariatric surgery:

  • food bypasses 90% of stomach, duodenum, and small segment of jejunum
  • possible complication: dumping sydnrome
A

roux-en-Y surgical procedure (RYGB)

35
Q

gastric foods emptying too rapidly into small intestine

A

dumping syndrome

36
Q

group of risk factors that increase a person’s chance of developing cardiovascular disease, stroke, diabetes (more prevalent in 60+ yo)

A

metabolic syndrome

37
Q

what are the criteria that someone must have 3 of to be considered to have metabolic syndrome (5)

A
  • waist circumference (40” + for men, 35” + for women)
  • triglycerides greater than 150
  • HDL cholesterol (less than 40 for men, less than 35 for women)
  • blood pressure greater than or equal to 130/85
  • fasting glucose greater than or equal to 100