lewis ch 40 - obesity Flashcards

1
Q

in what populations are obesity the highest (3)

A
  • in the south
  • black and hispanics
  • lower income and less educated
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2
Q

classification of obesity: excess caloric intake for body’s metabolic demands

A

primary obesity

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3
Q

classification of obesity: due to other preexisting health conditions

A

secondary obesity

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4
Q

what may cause secondary obesity (4)

A
  • chromosomal and genetic anomalies
  • metabolic problems
  • CNS lesions and disorders
  • drugs (corticosteroids, antipsychotics)
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5
Q

what hormones and peptides interact with the hypothalamus (5)

A
  • leptin (from adipocytes)
  • insulin (from pancreas)
  • ghrelin (from stomach)
  • peptide YY (from colon)
  • cholecystokinin (from small intestine)
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6
Q

enzyme that suppresses hunger and increases fat metabolism

A

leptin

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7
Q

enzyme that stimulates hunger and regulates it by inhibiting leptin

A

ghrelin

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8
Q

what can an increased production of adipokines lead to (3)

A
  • insulin resistance
  • dyslipidemia
  • hypertension
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9
Q

conditions associated with obesity that can improve with weight loss

A
  • hypertension
  • high cholesterol
  • sleep apnea
  • diabetes type 2
  • heart disease
  • gallbladder disease
  • osteoarthritis
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10
Q

what is the name for abdominal obesity

A

android obesity

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11
Q

what are android obesity patients are greater risk for developing (3)

A
  • increased LDLs
  • high triglycerides
  • decreased HDLs
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12
Q

what disease is obesity one of the most important preventable causes of

A

cancer

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13
Q

what two types of cancer are strongly related to obesity

A

breast cancer
endometrial cancer
(due to excess estrogen which is stored in fat cells)

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14
Q

4 ways to classify Body weight and obesity

A
  • body mass index (BMI)
  • waist circumference
  • waist to hip ratio (WHR)
  • body shape
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15
Q

what BMI is considered underweight

A

18.5 or less

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16
Q

what BMI range is considered normal

17
Q

what BMI range is considered overweight

18
Q

what BMI is considered obese

A

30 or greater

19
Q

what BMI is considered extremely obese

A

40 or greater

20
Q

people with visceral fat with android obesity are at increased risk for (2)

A

cardiovascular disease

metabolic syndrome

21
Q

what waist circumference is considered obese for men

22
Q

what waist circumference is considered obese for women

23
Q

what is the optimal waist to hip ratio

24
Q

two basic techniques in behavior modification that can be used to help treat obesity

A

self-monitoring

stimulus control

25
class of drugs that can be used to suppress appetite and treat obesity - high abuse potential - not recommended or approved by FDA
amphetamines
26
``` class of drugs that can be used to suppress appetite and treat obesity -recommended only for short term (3 months or less) ```
nonamphetamines
27
drug for treating obesity: - selective serotonin agonist - suppresses appetite and creates sense of satiety - side effects: headache, dizziness, fatigue, nausea, dry mouth, constipation
lorcaserin (belviq)
28
drug for treating obesity: - blocks fat breakdown and absorption in small intestine - inhibits action of intestinal lipases resulting in undigested fat being excreted in feces - side effects: stool leakage, severe liver injury may occur
orlistat (Alli)
29
what is the criteria for eligibility for bariatric surgery
- BMI greater or equal to 40 | - BMI greater or equal to 35 with other significant comorbidities
30
significant comorbidities (4) that combined with a BMI of 35 or greater can qualify someone for bariatric surgery
- hypertension - type 2 diabetes - heart failure - sleep apnea
31
3 broad categories of bariatric surgeries
- restrictive - malabsorptive - combination of restrictive and malabsorptive
32
type of restrictive bariatric surgery: | -limits stomach size with inflatable band around fundus of stomach
adjustable gastric binding (AGB)
33
type of malabsorptive bariatric surgery: - 75% of stomach is removed - nonreversible - results in elimination of ghrelin
sleeve gastrectomy
34
type of combination of restrictive and malabsorptive bariatric surgery: - food bypasses 90% of stomach, duodenum, and small segment of jejunum - possible complication: dumping sydnrome
roux-en-Y surgical procedure (RYGB)
35
gastric foods emptying too rapidly into small intestine
dumping syndrome
36
group of risk factors that increase a person's chance of developing cardiovascular disease, stroke, diabetes (more prevalent in 60+ yo)
metabolic syndrome
37
what are the criteria that someone must have 3 of to be considered to have metabolic syndrome (5)
- waist circumference (40" + for men, 35" + for women) - triglycerides greater than 150 - HDL cholesterol (less than 40 for men, less than 35 for women) - blood pressure greater than or equal to 130/85 - fasting glucose greater than or equal to 100