Lecture - Resp (Napper Histology) Flashcards
Conducting portion - epithelium
- What is the resp epithelium here? (your pneumonic)
- What are the cells that sit on the basemement membrane called and what is their function?
- What do the goblet cells do?
- There are two other type of cells here, what are they?
- one can be identified by having lots of dense granules
- the other can be identified bc it’s in the CT, I think
- Basal cells and they are probably proliferative
Olfactory epithelium
- What do the olfactory cells look like?
- what is at the bottom on the air interface? (long ____ _____) - What does the epithelium here look like?
- What are the tow types of basal cells?
- SO how many olfactory progenitor/stem cell types are there?
- are the GBC, HBCs pluripotent or multipotent
- what’s the function of having something that can regenerate in this area (slide 10) - How long does it take for them to divide and mature?
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Olfactory epithelium stem cells
- Alright so the olfactory mucosa is a rich source of what?
- what does the GBC turn into? HBC can also generate this
- what is HBC negative for neuronal markers - why? - Where do the MSC reside?
- what are they capable of?
Trachea in section
- What does the trachea look like in cross section?
- what is the distinct supporting tissue? - How is the mucosa different to esophagus?
Trachea - tissue and function
- What is the epitheloum type?
- What does the mucosal tissue (CT) contain? Two things - logically, what’s the function of these two things?
- What do you have in the submucosal surface?
- what does that produce to moisten the airwyas and trap the particular matter - Lastly, why is there cartialge?
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Bronchi
- The organisation and function of this is similar to trachea but there is a decrease in what?
- What are the changes in cf trachea:
- epithelium
- cartialge
- SM
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Trachea epithelium as seen by SEM:
What two types of cells can you see in this image and what are their functions in the trachea?
Motile cilia
They develop waves of movement - what do they move and in what direction?
Changes in resp epithelium
- When you have chronic coughing eg due to smoker’s cough, what happens to the epithelium?
- What cells produce the alternative types of epithelial cell
- What is the new epithelium?
- Why is the new epithelium less effective?
Okay slide 23 is the summary slide, so I’m going to ask you how far down these go:
- goblet cells
- cilliated cells
- glands
- hyaline cartilage
- SM
- elastic fibres
Bronchioles
- They are branching tubular structures less than ____ in diameter that terminate into _____ ____
- What is their epithelium?
- why do they still have cillia?
- why do only the biggest bronchioles have the goblet cells? - What are clara cells?
- what’s their function?
- do they have cilia? - Is the SM in the bronchioles really thick or really thin?
- Do you find cartilage in the bronchioles?
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Terminal bronchioles
- What is their epithelium
- Do they contain goblet cells
- They contain clara cells just like the resp bronchioles - what’s the purpose of this?
- what is the protein used that is released by the clara cells as a for?
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In the resiratory portion like in the alveolar sacs, what are the small alveolar pores for?
Alveoli
- What are the three types of cells they contain and what’re their functions?
- In this image, what do you see?
- How many basement membranes in the blood gass barrier?
The type 2 pneymocyte in the alveoli - what does it release and what’s the purpose of that?
“surfactant storage and secretions from _______ ______”
-What’s the thing with reuptake of the surfactant?
