Lab Eval Thyroid Hormone Flashcards

1
Q

Most important test for thyroid function and screening test

A

TSH

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2
Q

Normal TSH range

A

0.5-5.0 mIU/L

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3
Q

Free T4 normal range

A

0.9-2.3 ng/dL

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4
Q

Total T4 normal range

A

5.5-12.5 μg/dL

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5
Q

Total T4 is affected by

A

TBG abnormality

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6
Q

Free T4 (FT4) biologically active form of T4; requires separation from carrier protein using

A

EQUILIBRIUM DIALYSIS

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7
Q

T3 uptake (T3U) normal range

A

25-38%

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8
Q

Reflects quantity of TBG and hormone attached to it

A

T3 uptake (T3U)

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9
Q

Formula for FTI

A

FTI = Total T4 x (T3 uptake / mean normal T3 value)

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10
Q

Normal FTI range

A

5.4 - 9.7

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11
Q

Free T3 normal range

A

210-440 pg/dL

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12
Q

Total T3 normal range

A

80-200 ng/dL

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13
Q

Biologically active form of T3

A

FT3

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14
Q

T3 is usually tested when levels of TSH and FT4 are?

A

TSH ↓ and FT4 is N

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15
Q

RAIU normal range at 24 hours

A

5-30%

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16
Q

RAIU measures thyroidal uptake of iodine after an oral dose of I-131

A

RAIU

17
Q

Anti-TPO marker for autoimmune disease; sensitive marker for Hashimoto’s thyroiditis

A

Anti-TPO

18
Q

TRAb/TSHRAb thyroid-stimulating antibodies positive in 85% of patients with Grave’s disease

A

TRAb/TSHRAb

19
Q

TSH ↓; FT4, Total T4/T3, T3U ↑

A

Primary Hyperthyroidism

20
Q

TSH ↓ indicates hyperthyroidism, TSH ↑ indicates hypothyroidism

A

TSH Regulation

21
Q

TSH ↑, FT4, Total T4/T3, T3U ↓

A

Primary Hypothyroidism

22
Q

TSH, FT4, Total T4/T3 ↑

A

Secondary Hyperthyroidism

23
Q

Normal TSH, FT4, Total T4/T3 ↑, T3U ↓

A

Euthyroid with Abnormally High TBG

24
Q

Normal TSH, FT4, Total T4/T3 ↓, T3U ↑

A

Euthyroid with Abnormally Low TBG