Kidney numbers (exam 5) Flashcards
The blood pressure at the beginning of a systemic capillary is almost always going to be
30 mmHg
The blood pressure at the end of a systemic capillary is almost always going to be
10 mmHg
Delta P of a systemic capillary
20 mmHg
The kidneys get ___% of our CO
20%
How much blood do the kidneys get in mL/min?
1100 mL / min
(20% of CO which is 5L)
Pressure gradient between the end of the capillaries and the right atrium
10 mmHg (VERY small)
What are our two main resistance vessels?
small arteries, arterioles
Cross sectional area of the aorta
2.5 cm squared
What vessel has the biggest cross sectional area? What is it?
capillaries, 2500 cm squared
Where is the vast majority of our blood stored? What % is stored there?
Systemic veins, 84%
Velocity will also be given to you in..
units/time
What is the PISF or hydrostatic pressure in ISF in mmHg
-3 mmHg
Average aortic BP
100 mmHg
What is the surface area of all of the capillaries in our body in meters squared?
500-700 square meters
Internal diameter of vena cavea?
3 cm
Total cross sectional area of BOTH vena cava?
18 cm^2
Internal diameter of arterioles
30 micrometers
How many cell layers thick are the capillaries?
1 endothelial cell layer thick
-Good for nutrient exchange
-NO vascular smooth muscle
Cross sectional areas from smallest to largest:
aorta < venae cava < small arteries < arterioles < small veins < venules < capillaries (biggest)
What is the plasma or capillary colloid osmotic pressure / oncotic pressure in mmHg? (πCAP)
28 mmHg
What is the interstitial fluid colloid osmotic pressure / oncotic pressure in mmHg? (πISF)
8 mmHg
If we move around the lymphatic system can pick up the amount of work they are doing by…
20-40X
Three main proteins that make up total oncotic pressure in the CV system in order of importance
- albumin
- globulins
- Fibrinogen
Name the two large proteins that hang out in the interstitial fluid
- Proteoglycan filaments
- Hyaluronic acid
collagen is also out here
Net filtration pressure at arteriolar end of a capillary in mmHg?
How did you get it?
13 mmHg
Take factors that favor filtration:
30 mmHg (Pcap) + 3 mmHg (Pisf made positive) + 8 mmHg (Oncotic pressure of ISF) = 41
Subtract things that oppose filtration (plasma oncotic pressure) - 28 mmHg
41-28 = 13 mmHg
Net filtration pressure at venular end of a capillary in mmHg?
How did you get it?
-7 mmHg
Take factors that favor filtration:
10 mmHg (Pcap) + 3 mmHg (Pisf made positive) + 8 mmHg (Oncotic pressure of ISF) = 21 mmHg
Subtract things that oppose filtration (plasma oncotic pressure) - 28 mmHg
21 - 28 = -7 mmHg
Average capillary blood pressure
17.3 mmHg
Average NFP throughout the entire capillary
0.3 mmHg
Take factors that favor filtration:
17.3 mmHg ( average Pcap) + 3 mmHg (Pisf made positive) + 8 mmHg (Oncotic pressure of ISF) =
17.3 + 3 + 8 =28.3 mmHg
Subtract things that oppose filtration (plasma oncotic pressure) - 28 mmHg
28.3 - 28 =0.3
MAP in renal artery
100 mmHg
MAP in renal vein (do not have to give an exact number)
very low, ~0-10
BP in glomerular capillaries
60 mmHg
(because the afferent arteriole is high resistance)
The BP in the glomerular capillaries is ___x the amount of pressure we have in the typical systemic capillary
2x
ALL the glomerular capillaries filtering fluid over the course of a minute gives you a total filtration rate in glomerular capillaries of..
125 mL / min
