Kidney numbers (exam 5)

Question 1

The blood pressure at the beginning of a systemic capillary is almost always going to be

Answer 1

30 mmHg

Question 2

The blood pressure at the end of a systemic capillary is almost always going to be

Answer 2

10 mmHg

Question 3

Delta P of a systemic capillary

Answer 3

20 mmHg

Question 4

The kidneys get ___% of our CO

Answer 4

20%

Question 5

How much blood do the kidneys get in mL/min?

Answer 5

1100 mL / min

(20% of CO which is 5L)

Question 6

Pressure gradient between the end of the capillaries and the right atrium

Answer 6

10 mmHg (VERY small)

Question 7

What are our two main resistance vessels?

Answer 7

small arteries, arterioles

Question 8

Cross sectional area of the aorta

Answer 8

2.5 cm squared

Question 9

What vessel has the biggest cross sectional area? What is it?

Answer 9

capillaries, 2500 cm squared

Question 10

Where is the vast majority of our blood stored? What % is stored there?

Answer 10

Systemic veins, 84%

Question 11

Velocity will also be given to you in..

Answer 11

units/time

Question 12

What is the PISF or hydrostatic pressure in ISF in mmHg

Answer 12

-3 mmHg

Question 13

Average aortic BP

Answer 13

100 mmHg

Question 14

What is the surface area of all of the capillaries in our body in meters squared?

Answer 14

500-700 square meters

Question 15

Internal diameter of vena cavea?

Answer 15

3 cm

Question 16

Total cross sectional area of BOTH vena cava?

Answer 16

18 cm^2

Question 17

Internal diameter of arterioles

Answer 17

30 micrometers

Question 18

How many cell layers thick are the capillaries?

Answer 18

1 endothelial cell layer thick

-Good for nutrient exchange
-NO vascular smooth muscle

Question 19

Cross sectional areas from smallest to largest:

Answer 19

aorta < venae cava < small arteries < arterioles < small veins < venules < capillaries (biggest)

Question 20

What is the plasma or capillary colloid osmotic pressure / oncotic pressure in mmHg? (πCAP)

Answer 20

28 mmHg

Question 21

What is the interstitial fluid colloid osmotic pressure / oncotic pressure in mmHg? (πISF)

Answer 21

8 mmHg

Question 22

If we move around the lymphatic system can pick up the amount of work they are doing by…

Answer 22

20-40X

Question 23

Three main proteins that make up total oncotic pressure in the CV system in order of importance

Answer 23

1. albumin
2. globulins
3. Fibrinogen

Question 24

Name the two large proteins that hang out in the interstitial fluid

Answer 24

1. Proteoglycan filaments
2. Hyaluronic acid

collagen is also out here

Question 25

Net filtration pressure at arteriolar end of a capillary in mmHg? How did you get it?

Answer 25

13 mmHg Take factors that favor filtration: 30 mmHg (Pcap) + 3 mmHg (Pisf made positive) + 8 mmHg (Oncotic pressure of ISF) = 41 Subtract things that oppose filtration (plasma oncotic pressure) - 28 mmHg 41-28 = 13 mmHg

Question 26

Net filtration pressure at venular end of a capillary in mmHg? How did you get it?

Answer 26

-7 mmHg Take factors that favor filtration: 10 mmHg (Pcap) + 3 mmHg (Pisf made positive) + 8 mmHg (Oncotic pressure of ISF) = 21 mmHg Subtract things that oppose filtration (plasma oncotic pressure) - 28 mmHg 21 - 28 = -7 mmHg

Question 27

Average capillary blood pressure

Answer 27

17.3 mmHg

Question 28

Average NFP throughout the entire capillary

Answer 28

0.3 mmHg Take factors that favor filtration: 17.3 mmHg ( average Pcap) + 3 mmHg (Pisf made positive) + 8 mmHg (Oncotic pressure of ISF) = 17.3 + 3 + 8 =28.3 mmHg Subtract things that oppose filtration (plasma oncotic pressure) - 28 mmHg 28.3 - 28 =0.3

Question 29

MAP in renal artery

Answer 29

100 mmHg

Question 30

MAP in renal vein (do not have to give an exact number)

Answer 30

very low, ~0-10

Question 31

BP in glomerular capillaries

Answer 31

60 mmHg (because the afferent arteriole is high resistance)

Question 32

The BP in the glomerular capillaries is ___x the amount of pressure we have in the typical systemic capillary

Answer 32

2x

Question 33

ALL the glomerular capillaries filtering fluid over the course of a minute gives you a total filtration rate in glomerular capillaries of..

Answer 33

125 mL / min