Intracellular Bacteria Flashcards

1
Q

where does the family Chlamydiaceae multiply?

A

vacuoles in eukaryotic cells

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2
Q

the infectious extracellular form, called the ____________________, initiates infection by attaching to an inducing uptake by the host cell

A

elementary body (EB)

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3
Q

one internalized, the bacteria remain within a membrane-bound vacuole where the organism differentiates into a more metabolically active form called the ________________________

A

reticulate body (RB)

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4
Q

are Rickettsiaceae obligate intracellular?

A

yes

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5
Q

Rickettsiaceae are commonly carried and transmitted by _______________________________________

A

arthropods like ticks, mites, lice, or fleas

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6
Q

what cells do Rickettsiaceae preferentially infect?

A

vascular endothelium

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7
Q

which Rickettsiaceae species is sgnificantly associated with animal disease?

A

Rickettsia rickettsii

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8
Q

what is the agent of rocky mountain spotted fever?

A

Rickettsia rickettsii

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9
Q

what is Coxiella burnetii the agent of?

A

Q fever

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10
Q

what are the primary reservoirs of Coxiella burnetii?

A

cattle
sheep
goats

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11
Q

how are Coxiella burnetii excreted?

A

milk
urine
feces

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12
Q

what is the disease like caused by Chlamydiaceae?

A

variable: clinically inapparent to severe systemic infections (fever, anorexia, lethargy, occasionally death)

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13
Q

what does Chlamydophila abortus cause?

A

enzootic abortion in ewes
also goats, cattle, pigs
pregnant women

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14
Q

what is Chlamydophila pecorum responsible for in farm animals?

A

polyarthritis and polyserositis in sheep, cattle, other animals
sporadic bovine encephalomyelitis

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15
Q

with Chlamydophila pecorum, both ________________________ tissue changes can be seen in the joints

A

periarticular and articular

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16
Q

what does Chlamydophila felis cause?

A

conjunctivitis in cats

17
Q

what does Chlamydophila psittaci cause?

A

avian chlamydiosis: fibrinous serositis of body cavities, air sacs, and organ surfaces
lung, liver, spleen are enlarged and congested

18
Q

what diseases does Chlamydophila psittaci cause?

A

ornithosis
psittacosis
avain chlamydiosis

19
Q

what was the level of infection found with Chlamydophila pecorum and C. pneumoniae found in wild koalas?

A

C. pecorum ranged from low to high grade
C. pneumoniae always low grade

20
Q

what is the drug of choice for chlamydial infections?

A

tetracycline

21
Q

what is trachoma?

A

disease caused my Chlamydia trachomatis
leading cause of preventable blindness

22
Q

what does Chlamydophila pecorum cause in koalas?

A

inflammatory and fibrotic disease in the eye and the urogenital and reproductive tracts in koalas

23
Q

what carries Rickettsia rickettsii?

A

20 species of ixodid ticks

24
Q

how do ticks become infected with Rickettsia rickettsii?

A

female can transmit to eggs transovarially
feed on blood from host in larval or nymphal stage
male ticks can transfer to females during mating

25
what are the early signs of Rickettsia rickettsii?
high fever vomiting diarrhea hemorrhagic mucous membranes
26
where do Coxiella burnetii replicate?
inside phagolysosome phagosome-containing bacteria within cell fuse with lysosomes to form
27
what is unique about the reproductive cycle of Chlamydiaceae?
infectious and reproductive forms are morphologically distinct
28
what are the two genera in Chlamydiaceae?
Chlamydia Chlamydophila
29
what is usually present in the enzootic abortion of ewes caused by Chlamydophila abortus?
necrosis of cotyledonss and edema of intercotyledon tissue dirty pink uterine exudate
30
what is sporadic bovine encephalomyelitis caused by?
Chlamydophila pecorum
31
does Chlamydophila psittaci cause fibrinous serositis?
yes
32
what is the more pathogenic Chlamydophila spp that infect koalas?
C. pecorum