Diseases Due to Gram Negative Rods IV Flashcards
what is the appearance of Pasteurellaceae?
gram negative rods/coccobacilli
bipolar staining: safety pin
are Pasteruellaceae motile?
no
how stable are Pasteurellaceae in the environment?
unstable
is Pasteurellaceae commensal?
yes: upper respiratory tract mucosae mostly
describe Pasteurella multocida: hemolytic or not and capsule
non-hemolytic
thick capsule
describe Mannheimia haemolytica: former name, hemolytic or not, who it infects
Pasteurella haemolytica
hemolytic
ruminants
is Histophilus/Haemophilus heamolytic?
haemolytic or non-haemolytic
does Pasteurellaceae have flagella?
no
what virulence factors does Pasteurellaceae have for adherence?
adhesions
fimbriae
filamentous haemagglutinins
what makes up the capsule antiphagocytic effect of Pasteurellaceae?
hylauronic acid
heparin
chondroitin
looks like the host
Pasteurella multocida colonizes ___________________________
ciliated respiratory epithelial cells
what does Pasteurella multocida cause in cattle?
shipping fever
enzootic pneumonia of calves
mastitis
septicemia
what is atrophic rhinitis of swine caused by?
Pasteurella multocida type D
how is Pasteurella multocida transmitted in swine?
inhalation
from sow
aerosols
how is Pasteurella multocida controlled in swine?
vaccine
what is Pasteurella multocida often mixed with in swine?
Bordatella bronchiseptica
what causes fowl cholera in birds?
Pasteurella multocida type F
who does fowl cholera impact?
turkeys
chickens
wild fowl
what is the acute form of fowl cholera/Pasteurella multocida in birds?
septicemia to fatal in 6-12 hours
what causes snuffles in rabbits?
Pasteurella multocida type A
+/- Staphylococcus
is Pasteurella multocida in rabbits opportunistic?
yes: transport, overcrowding, cole, poor ventilation
what are the sequelae with snuffles in rabbits?
bronchopneumonia
conjunctivitis
otitis
abscesses
what is the treatment for snuffles in rabbits?
antibiotics
is Pasteurella multocida zoonotic?
yes: bites, scratches
describe the appearance of Bartonella henselae
gram negative rod
what is the zoonotic importance of Bartonella henselae?
cat scratch disease: scratching, biting, or licking wounds/scabs
what can cat scratch disease affect?
brain
eyes
heart
other internal organs
what causes bovine respiratory disease (BRD)?
Mannheimia haemolytica
Pasteurella multocida
H. somni
M. bovis
predisposing event
what are the morbidity and mortality of bovine respiratory disease?
30-50%
1-10%
how is bovine respiratory disease controlled?
antibiotics
vaccine
stress reduction
what causes pneumonic pasteurellosis in sheep?
Mannheimia haemolytica
sporadically Pasteurella multocida
what characterizes the acute form of pneumonic pasteurellosis in young sheep?
fever
respiratory distress
sudden death
what can cause septicemia in lambs?
Mannheimia haemolytica
Bibersteinia trehalosi
what causes septicemia in cattle and bison?
Pasteurella multocida types B and E
does Histophilus somni survive well in the environment?
yes: 70 days
what is the acute form of Histophilus somni like?
septicemia
thromboembolic meningoencephalitis
blindness
ataxia
myocarditis
pneumonia
sudden death
what causes glasser disease?
Haemophilus parasuis
who does glasser disease impact?
swine
how is Haemophilus parasuis transmitted in swine?
from sow: aeerosol inhalation, direct contact
how is glasser disease controlled?
antibiotics
multivalent vaccines
stress reduction
which Bordatella infects humans?
Bordatella pertussis: whooping cough
what does Bordatella look like under a microscope with a gram stain?
gram negative rods or coccobacilli
is Bordatella commensal?
yes: upper respiratory tract mucosa
true/false: Bordatella is always localized and never systemic
true
who does Bordatella parapertussis infect?
lambs: pneumonia
how can infection with Pasteurellaceae occur?
endogenous or exogenous
what are some commensals that cause disease when local or systemic host immunity is compromised?
Pasteurella
Mannheimia
Histophilus/Haemophilus
what is the pathogenesis of Pasteurellaceae?
adherence: adhesions, fimbriae, filameentouss haemagglutinins
no flagella
capsule: hyaluronic acid, heparin, chondroitin
siderophores
endotoxins
exotoxins
what cells does Mannheimia haemolytica colonize?
ciliated respiratory epithelial cells
what is the acute form of pneumonic pasteurellosis like in adult sheep?
mastitis
what is Histophilus somni a commensal of?
bovine genital and respiratory tracts
