(F) Cestodes: Cont. of Cyclophyllidea (module-based) Flashcards
- It has a cosmopolitan distribution but more common in warm than cold countries
- a common tapeworm of man in Hawaii
- It is the only tapeworm that does not need, or utilize, an intermediate host.
HYMENOLEPIS NANA
HYMENOLEPIS NANA
AKA
dwarf tapeworm
HYMENOLEPIS NANA
Adult worm inhabits where?
be espisipik
upper 2/3rd of the ileum
HYMENOLEPIS NANA
TOF. It has a lifespan of several days.
F (weeks)
HYMENOLEPIS NANA: MORPHOLOGY
Adult worms measure up to?
40mm long
HYMENOLEPIS NANA: MORPHOLOGY
Scolex
* Rhomboid scolex with how many cup-like suckers?
* (short/long) rostellum with (number) of spines ARRANGED in a SINGLE RING
- 4
- Short (20-40 spines)
HYMENOLEPIS NANA: MORPHOLOGY
Which does not belong in the immature segment
A. Short and narrow
B. Broad proglottids
C. Most distal segments are pointy
D. NOTA
C (all are correct except C, it is rounded)
HYMENOLEPIS NANA: MORPHOLOGY
In what segment are three (3) rounded testes, a bi-lobed ovary, and saccular uterus are found?
Mature segments
HYMENOLEPIS NANA: MORPHOLOGY
- 30 - 47 um in diameter
- Spherical or sub-spherical, oncosphere (hexacanth embryo) enclosed in an inner envelope with 2 polar thickenings having 4 - 8 polar filaments each
Egg
HYMENOLEPIS NANA: MORPHOLOGY
The presence of what part is diagnostic and serves to differentiate H. nana egg from that of H. diminuta?
located in the egg
polar filaments
HYMENOLEPIS NANA: MORPHOLOGY
No. of polar filaments
4-8
HYMENOLEPIS NANA: LIFE CYCLE
MOT of Man
- Ingestion of viable embryonated eggs
- Person-to-person contact
- Hand-to-mouth transfer
- Vector (possibly, accidental intermediate host)
- Contaminated food or water
HYMENOLEPIS NANA: LIFE CYCLE
The embryonated eggs hatch where in the body?
stomach or small intestine
HYMENOLEPIS NANA: LIFE CYCLE
After hatching, the freed oncosphere penetrates the villi of the anterior part of the small intestine where, after a few days, it develops into a?
cysticercoid larva
HYMENOLEPIS NANA: LIFE CYCLE
Days of Maturation
2 weeks
larva na siya kaya pwede na siya magproduce ng egg
HYMENOLEPIS NANA: LIFE CYCLE
How are eggs released if there is no uterine pore?
Apolysis
Disintegration of most distal proglottids (kung nasaan yung gravid segment)
HYMENOLEPIS NANA: CLINICAL MANIFESTATION
TOF. Generally, the infection is usually well tolerated even among patients with heavy worm load and clinical manifestation is often due to allergic reactions.
T
HYMENOLEPIS NANA: CLINICAL MANIFESTATION
Patients may manifest? (6)
- headache
- dizziness
- anorexia
- pruritus of nose and anus
- periodic diarrhea
- abdominal distress
HYMENOLEPIS NANA: CLINICAL MANIFESTATION
Children may manifest (4)
- lack of appetite
- abdominal pain
- with or without diarrhea
- vomiting, and dizziness
HYMENOLEPIS NANA
Lab diagnosis
DFS
HYMENOLEPIS NANA
Treatment and Prevention available
- Treatment: niclosamide, praziquantel and paromomycin
- Measures: improve the hygiene habits, especially among children, environmental sanitation, proper and safe human waste disposal, and effective methods of rodent control
HYMENOLEPIS DIMINUTA
AKA
commonly called the rat tapeworm
HYMENOLEPIS DIMINUTA
MOT
- accidental ingestion of an intermediate host (may be present in foods, flour, or hands that contains the cysticercoid larva)
HYMENOLEPIS DIMINUTA
Intermediate hosts
Fleas
fleas fleas fleas
Ctenocephalides canis (dog flea), Ctenocephalides felis (cat flea), Xeonpsylla cheopis and Nosopsyllus fasciatus (rat flea), and Pulex irritans (human flea)
HYMENOLEPIS DIMINUTA: LIFE CYCLE
Inhabit
Small intestine
HYMENOLEPIS DIMINUTA: LIFE CYCLE
MOT of intermediate host
intermediate hosts ingest the mature eggs that may have been discharged in the environment together with the feces (by the definitive host)
HYMENOLEPIS DIMINUTA: LIFE CYCLE
The liberated oncosphere penetrates what part of the insect to mature into an infective stage to the definitive host?
hemocele
HYMENOLEPIS DIMINUTA: CLINICAL MANIFESTATION
TOF. Well tolerated by man always.
F (oftentimes)
HYMENOLEPIS DIMINUTA: CLINICAL MANIFESTATION
TOF. Most infected individuals are symptomatic.
F (a simp)
HYMENOLEPIS DIMINUTA: CLINICAL MANIFESTATION
Some patients may experience (anorexia/obesity)
anorexia
kainin mo raw to para pumayat ka
HYMENOLEPIS DIMINUTA
LAB DIAGNOSIS
Diagnosis can be conformed thru recovery of eggs in fecal specimens.
HYMENOLEPIS DIMINUTA
Treatment and Prevention
- Treatment: Praziquantel and niclosamide
- Measures: (1) Avoid exposure to the intermediate host (2) Control measures to eradicate the intermediate host (3) Proper disposal of human excreta (4) Rodent control (5) Early diagnosis and prompt treatment of infected individuals
- causes dipylidiasis or dog tapeworm infection
- common tapeworm of dogs and cats throughout the world
DIPYLIDIUM CANINUM
DIPYLIDIUM CANINUM
AKA
double pored dog tapeworm
double pored dog tapeworm
Adult worm inhabits where?
small intestine of the definitive host
DIPYLIDIUM CANINUM: LIFE CYCLE
Eggs that hatch in the intestine of these arthropods develop into?
procercoid larva
DIPYLIDIUM CANINUM: LIFE CYCLE
MOT
Ingestion of cysticercoid larva
in the body of the arthropod intermediate host
DIPYLIDIUM CANINUM: LIFE CYCLE
Days of Maturation in man
3-4 weeks
DIPYLIDIUM CANINUM: LIFE CYCLE
The procercoid larva later transform into what stage in the body of the adult flea?
cysticercoid larva
DIPYLIDIUM CANINUM: LIFE CYCLE
definitive hosts
Dogs
Cats
Man (occasionally)
DIPYLIDIUM CANINUM: LIFE CYCLE
Intermediate host
- Ctenocephalides canis
- Ctenocephalides felis
- Pulex irritans
- Trichodectes canis (dog louse)
DIPYLIDIUM CANINUM: LIFE CYCLE
All cases were among children ingesting the infected dog or cat fleas because?
they kiss or are licked by infected pets
DIPYLIDIUM CANINUM: CLINICAL MANIFESTATION
Symptoms among children (mild)
- light intestinal disturbances, (indigestion, abdominal pain, loss of appetite, diarrhea)
- Anal itchiness due to migrating segments
DIPYLIDIUM CANINUM:
LAB DIAGNOSIS
- Recovery and identification of eggs, contained in a capsule (diagnostic) in direct fecal smear and/or the gravid (may also include mature) segments will confirm the diagnosis
DIPYLIDIUM CANINUM:
Treatment and prevention
- Treatment: Niclosamide and praziquantel
- Preventive measures: control of dog and/or cat fleas, regular cleaning of dogs, cats, and other animals in or near the house, early diagnosis and prompt treatment of infected persons and proper disposal of human excreta
- Causes unilocular echinococcosis or hydatid disease among humans
- Man does not harbor adult worms.
- Human infection is limited
- Most extensive and intensive enzootic endemic regions are sheep and/or cattle raising countries
- Prevelance depends on intimate association of humans with infected dogs
- Dog owners have a greater risk of infection than non-owners or dogs
- Adult worms are attached at the mucosal wall of the small intestine of dogs, wolves, jackals, coyotes, foxes, and other carnivores
Echinococcus granulosus
Echinococcus granulosus
AKA
hydatid worm
Echinococcus granulosus: Life Cycle
Definitive host
Dog
Echinococcus granulosus: Life Cycle
MOT
Ingestion on the viscere of an intermediate host infected with hydatid larvae
Echinococcus granulosus: Life Cycle
Intermediate host
Sheep, goat, camel, ox, hog, cattle, man and other suitable intermediate hosts
Echinococcus granulosus: Life Cycle
Hatch (Inter. host)
Duodenum of the intermediate host
Echinococcus granulosus: Life Cycle
There two types of cycle:
- Pastoral
- Sylvatic
Echinococcus granulosus: Life Cycle
MOT to huamns
- ingestion of the eggs, which is chiefly a hand-to-mouth transfer
Echinococcus granulosus: Pathogenesis
Cysts may be distributed in?
organ
Liver
may include secondary peritoneal invasion, lungs, kidneys, bones, brain, and other tissues such as muscle, spleen, eyes, heart, and thyroid
Echinococcus granulosus: Pathogenesis
adjacent tissues undergo atrophy and pressure necrosis occurs due to?
growing cyst
which can also cause vascular constriction
Echinococcus granulosus: Pathogenesis
- evoke inflammatory reactions to surrounding tissues that produce encapsulating fibrous adventitia.
- impairs an organ mainly due to mechanical pressure
Unilocular cyst
Echinococcus granulosus: Clinical Manifestation
Echinococcus granulosus: Clinical Manifestation
Cyst at the dome of the liver grows slowly and persists even as long as how many years before producing noticeable symptoms?
30
Echinococcus granulosus: Clinical Manifestation
Pressure on bile ducts may result to?
obstructive jaundice and on the ureters
Echinococcus granulosus: Clinical Manifestation
triad of manifestations in cases of biliary duct obstruction includes
- Jaundice
- Fever
- Eosinophilia
Echinococcus granulosus: Clinical Manifestation
Early manifestations
slight hemoptysis, cough, dyspnea, transient thoracic pain, palpitation, tachy-cardia, and pruritus.
familiarize ka lang kapag mga ganito ok
Echinococcus granulosus: Clinical Manifestation
may produce intermittent pain, hematuria, and kidney dysfunction
anong cyst
Renal cyst
Echinococcus granulosus: Clinical Manifestation
Echinococcus granulosus: Clinical Manifestation
increase intracranial pressure and Jacksonian type of epilepsy
A. Osseous hydatid
B. Renal cyst
C. Brain cyst
D. Splenic cyst
C
may produce dull pain and bulging of the ribs, whereas spotty areas of dullness and resonance on percussion may be demonstrated with pelvic cysts
splenic cyst
ECHINOCOCCUS GRANULOSUS
Laboratory Diagnosis
- Radiologic examinations such as X-ray, CT-scan, and ultrasonography
- Demonstration of protoscolices, brood capsules and/or daughter cysts after surgical removal
- Hydatid fragments in sputum or urine
- Serologic tests can also be used, this include E.L.I.S.A., H.I.A., Indirect Fluorescent Antibody (IFA), and IEP (Immune electrophoresis).
Lifecycle: D. granulosus
- Intermediate host are chiefly herbivores, in whose organs and tissues, the larval form becomes unilocular hydatid cyst.
- Occurs in wolves
- The most important host is sheep.
- Hydatid cyst develops in wild ungulates (moose and reindeer) and human are less likely to become infected as accidental host.
A. Sylvatic
B. Pastoral
BABA