Exam 3 – Lecture 21: Hemic-Lymphatic 2 Flashcards
What are the cells in reticular meshwork of a lymph node?
Reticular cells
Dendritic cells
Macrophages
Follicular dendritic cells
What are reticular cells?
Collagen III = reticular fibers
What are dendritic cells?
Antigen presenters in T areas
What are macrophages?
Phagocytes that present antigen
Where are follicular dendritic cells?
B areas
What do DCs do with antigen?
Pass them onto the lymphoid
What do follicular DCs have?
Extensive cytoplasmic processes
What occurs in high endothelial venules?
Fluid resorption
Circulating lymphocytes enter exit lymph nodes here
Where is the only place the high endothelial venules exist?
Lymph nodes
What kind of organ is the thymus?
Lymphoepithelial
Where is the thymus located?
Anterior mediastinum/thoracic inlet
What age animals have a thymus?
Young
What happens in the thymus?
T-lymphocyte development
What are “sweet-breads”?
Thymus or pancreas at a butcher shop
What is a thymus made of?
Capsule
Trabeculae–––lobules
What cells are found in the thymus?
Thymocytes
Epithelioreticular cells (types I-VI)
Macrophages
What do thymocytes do?
Develop T lymphocytes
Where are thymic corpuscles found?
In the medulla of the thymus
What are thymic corpuscles?
Keratinized rings
Epithelial component of the thymus
What makes up the blood-thymus barrier?
Endothelium
Macrophages
Type I epithelioreticular cells
Where is the spleen located?
Abdomen, near the stomach
What does the spleen look like?
Oval, round, or triangular
Mesh-like, so that when smooth muscle contracts a lot of blood can be pushed out of the spleen
What does the spleen do?
Filters, stores, and removes blood
Antigen processing
What makes up the spleen?
Fibromuscular capsule and trabeculae
Hilus that attaches to the splenic ligament
Red pulp and white pulp
Where does the capsule descend to? What does it become?
Down into the spleen and becomes trabeculae
What does red pulp of the spleen do?
Filtration/degradation
What is the red pulp of the spleen like?
Rod-shaped endothelium
What can be found in red pulp?
Macrophages for surveillance
Describe white pulp of the spleen
Numerous (mostly) lymphocytes
Has a central artery
Has nodules
What is the central artery in white pulp?
A branch of splenic artery
