Exam 1 – Lecture 8: Connective Tissue 2 Flashcards

1
Q

What are reticular fibers?

A

Support structure of various organs (especially hemopoeitic and lymphoid organs)

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2
Q

What kind of pattern do reticular fibers make?

A

Mesh-like (reticulated)

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3
Q

What are elastic fibers like?

A

Linear, stretchy, and coiled

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4
Q

What are elastic fibers made out of?

A

Elastin and fibrillin

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5
Q

What do elastic fibers make up?

A

Vertebral ligaments, larynx, elastic arteries

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6
Q

What is the extracellular matrix?

A

Everything outside of cells

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7
Q

What ground substance makes up the extracellular matrix?

A

Proteoglycans
Multi adhesive glycoproteins
Glycosaminoglycans

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8
Q

What does the extracellular matrix do?

A

Support and communications

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9
Q

What are the 2 types of connective tissue categories?

A

Loose

Dense

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10
Q

Describe loose connective tissue

A

Loosely arranged fibers

Abundant, various cell types

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11
Q

What are the 2 types of dense connective tissue?

A

Irregular and regular

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12
Q

Describe irregular dense connective tissue

A
Many fibers, few cells
Lamina propria (beneath epithelia), matrix for blood vessels
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13
Q

Describe regular connective tissue

A

Ordered, densely packed fiber cells

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14
Q

What are the types of cells in connective tissue?

A
Fibroblast
Macrophages
Adipocytes
Mast cells
Transient WBCs
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15
Q

What is the main cell of connective tissue?

A

Fibroblast

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16
Q

What do fibroblasts produce?

A

Collagen

17
Q

What is the mature cell type of fibroblasts?

A

Fibrocytes

18
Q

What is a myofibroblast?

A

A fibroblast with muscle-type components

19
Q

What are myofibroblasts a pat of?

A

Healing, allows scars to shrink

20
Q

Describe macrophages

A

Resident phagocytes
Large, 25-30 microns
“Bean-shaped” nucleus
Abundant amphiphilic cytoplasm

21
Q

Describe mast cells/basophils

A

Rare, discrete cells
Prominent basophilic granules
Bone marrow origin

22
Q

Where do you tend to find mast cells/basophils?

A

Skin, mucous membranes in allergic organs

23
Q

What do mast cells/basophils produce?

A

Vasoactive substances

24
Q

What vasoactive substance do mast cells/basophils produce?

A

Histamine
Heparin
Leukotrienes
Eosinophil chemotactic factor

25
Q

What do adipocytes do?

A

Energy storage

26
Q

Where are adipocytes located?

A

Subcutaneous, internal organs